For each of the following antibiotics, determine how many moles of each compound are present for the given mass. What quantity in moles of tetracycline (C22H24N2O8) are in 77.9 grams?
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- Write a paragraph explaining the meaning of the phrase "Its dose that makes the poison". Supoort your answer with examples of your own.1. Penicillin is hydrolyzed and thereby rendered inactive penicillinase, an enzyme present in some penicillin-resistant bacteria. The molecular weight of this enzyme in Staphylococcus aureus is 29.6 kilo Daltons (29.6 kg/mole or 29,600 g/mole or 29,600 ng/nmole) The amount of penicillin hydrolyzed in 2 minute in a 10-mL solution containing 109 g (1 ng) of purified penicillinase was measured as a function of the concentration of penicillin. Assume that the concentration of penicillin does not change appreciably during the assay. [Hint: Convert everything to the same concentration terms] Show all calculations and include spreadsheets and graphs to determine Km, Vmax and kcat for this enzyme. Make sure your final answers have correct units. [Another hint: Note that [S] and amount hydrolyzed are already in concentration terms. So you don't need to worry about the volume for calculating [S] and V. ] Penicillin concentration (microM) Amount hydrolyzed (nanoM) 1 110 3 250 5 340 10 450 30 580…Course Home ollege.com/course.html?courseld=D15807691&OpenVellumHMAC=9c87262d9de99faf53f1782b38312140#10001How do you calculate the reference doses for lead and naphthalene?The LD50 of ethlyl alcohol (ethanol) is 5 g/kg How many beers could a 164 pound student consume before reaching a lethal dose (ignoring pharmacogenomics and tolerance)?The LD50 of a substance is the concentration at which a substance will kill half of a test specimen. What doesLD50 stand for? * O Low Dose 50 O Limit Dosage 50 O Lethal Dose 50 O Legal Dosage 50The active ingredient of Benadryl© Chesty Forte Cough Liquid is Guaiphenesin anexpectorant drug used to assist the expectoration ('bringing up') of phlegm from theairways in acute respiratory tract infections. A 200.0 mL bottle of Benadryl© ChestyForte Cough contains 4.00 g of Guaiphenesin (C10H14O4). i. If the recommended dose for a child is 150 mg of Guaiphenesin. What volume of thecough liquid should be administered?The active ingredient of Benadryl© Chesty Forte Cough Liquid is Guaiphenesin anexpectorant drug used to assist the expectoration ('bringing up') of phlegm from theairways in acute respiratory tract infections. A 200.0 mL bottle of Benadryl© ChestyForte Cough contains 4.00 g of Guaiphenesin (C10H14O4). i. If the recommended dose for a child is 150 mg of Guaiphenesin. What volume of thecough liquid should be administered? ii. If the recommended dose for an adult is 350 mg of Guaiphenesin. How many molesof Guaiphenesin does this equal? (answer to 2 significant figures).The LD50 of ethlyl alcohol (ethanol) is 5 g/kg a.) How many grams of ethanol would constitute a lethal dose for an adult weighing 164pounds?The active ingredient of Benadryl© Chesty Forte Cough Liquid is Guaiphenesin anexpectorant drug used to assist the expectoration ('bringing up') of phlegm from theairways in acute respiratory tract infections. A 200.0 mL bottle of Benadryl© ChestyForte Cough contains 4.00 g of Guaiphenesin (C10H14O4). i. If the recommended dose for a child is 150 mg of Guaiphenesin. What volume of thecough liquid should be administered? ii. If the recommended dose for an adult is 350 mg of Guaiphenesin. How many molesof Guaiphenesin does this equal?Why are sharp knives more effective than dull knives ?Describe the following substances with one suitable example of each type: (i) Non-ionic detergents (ii) DisinfectantsSEE MORE QUESTIONS
