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- Example 5 Anti-A 0 Problem: Causes: Resolution: Anti-B 2+mf A1 Cells 3+ B Cells 0B2. During a mass spectrometry experiment, the spectrum of vascular endothelial growth factor A (VEGF-A) was acquired. The absolute error of VEGF-A, having a mass of 1024.5210 Da was 0.06 Da. Calculate the relative error (ppm). (10 marks)5 1 point What are the units used to measure the concentration of phage in a lysate? plaques/uL Oplaques/mL plaque forming units/mL plaque forming units/uL Previous
- talk about Von willebrand factor test Within two pages4 Natalizumab is a therapeutic monoclonal antibody that targets the cell- adhesion molecule a4-integrin and is used as a second-line therapy for severe Crohn's disease. What might be its mechanism of action?explain the most likely steps of what might happen inside a MDA-MB-231 cell after it is exposed to UV light.
- 1) Explain the principle of the electrical impedance cell counting. 2) State 3 Haematology analyzer and their manufacturers. 3) CV for automated instrument is +/- 1% to +/- 2% compared to manual count with CV +/- 10%. Can you explain their differences?22:23 1O 000 · 11:24 A9 OB1 r ll l 52% . +964 782 734 3923 2m541139927815107... Patient Encounter Part 3 The pretreatment workup is summarized below. Pathology: 47-year-old female with new diagnosis of infiltrating intraductal adenocarcinoma involving the left breast and regional node. Further tests on tumor samples indicated ER (8%), PR (negative), HER2 (negative), Ki-67 (72%), and grade (poorly differentiated). Intrinsic subtype (luminal B, HER2-negative). Radiology: FDG-PET/CT indicated a 5.3 x 2.5 cm mass in the left breast which appeared to extend to the epidermis of the skin; one node in the left axilla was also involved with tumor. No other evidence of distant disease was visualized. Laboratory: CBC, liver, and kidney function tests WNL, alkaline phosphatase and calcium are normal also. Stage: IB (T, N, M,) List the most important prognostic factors in this patient with newly diagnosed breast cancer. Assess the patient's level of risk for relapse. 50 SECTION 16 | ONCOLOGIC…B. The concentration profile of drug diffusion in a tumor spheroid is given by: Qr3 ди + C = r². 3D ar a. Derive an equation for u in terms of r b. Find u, when drug dissolves only to 10% from the surface of the spheroid (assume the radius of the spheroid as b; the concentration of drug at the surface as up). c. Plot the tumor spheroid concentration profile.
- What is the working principle of Lateral flowimmunochromatographic assays (LFIAs)? Supported with a figure and reference plzCompare and contrast GPCRs with RTK. Please keep brief - 10 sentences/dot points max.Cancer stem cells (CSCs) are cancer cells (found within tumors or hematological cancers) that possess characteristics associated with normal stem cells, specifically the ability to give rise to all cell types found in a particular cancer sample. There are many biomedical engineering based approaches to detect CSCs. 1) What is the importance and advanatge of detecting CSCs? 2) What kind of systems have been developed to detect CSCs? Describe by giving examples.