er discussing his case with his physician, he learned that he had probably been the victim of pufferfish poisoning. The active toxin in the tissues of this fish is a chemical called tetrodotoxin (TTX). Tetrodotoxin is in a class of chemicals known as neurotoxins because it exerts its effects on neurons. The specific action of tetrodotoxin is that it blocks voltage-gated sodium ion channels. Define the following phrases and terms associated with the signs and symptoms of Dr. Westwood’s TTX poisoning: diaphoresis motor dysfunction paresthesias cyanotic hypoventilating  bradycardia

Principles Of Pharmacology Med Assist
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ISBN:9781337512442
Author:RICE
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Chapter8: Forms Of Drugs And How They Act
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After discussing his case with his physician, he learned that he had probably been the victim of pufferfish poisoning. The active toxin in the tissues of this fish is a chemical called tetrodotoxin (TTX). Tetrodotoxin is in a class of chemicals known as neurotoxins because it exerts its effects on neurons. The specific action of tetrodotoxin is that it blocks voltage-gated sodium ion channels.

  1. Define the following phrases and terms associated with the signs and symptoms of Dr. Westwood’s TTX poisoning:
    1. diaphoresis
    2. motor dysfunction
    3. paresthesias
    4. cyanotic
    5. hypoventilating 
    6. bradycardia
    7. gastric lavage
    8. oxygen saturation
  2. As mentioned in the case description, tetrodotoxin is a molecule that blocks voltage-gated sodium ion channels. What is a voltage-gated sodium ion channel and what is its function?. 

 

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