Describe the prokaryotic translation initiation shown in the diagram. Define the convention of protein synthesis (directionality of synthesis) as well as the meaning of the A, P, and E sites of the ribosome.

Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter29: Transcription And The Regulation Of Gene Expression
Section: Chapter Questions
Problem 3P: Substrate Binding by RNA Polymerase RNA polymerase has t binding sites for ribonucleoside...
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Describe the prokaryotic translation initiation shown in the diagram. Define the convention of protein synthesis (directionality of synthesis) as well as the meaning of the A, P, and E sites of the ribosome. 

A
IF-3
30S subunit
3'
5'
MRNA transcript
AUG
Shine-Dalgarno
Sequence
В
fMet-TRNA;
fMet
IF-2-
GTP
IF-1
3'
AUG
5'
50S subunit
fMet
A
GTP
AUG
fMet
GDP + Pi
IF-1
IF-2
IF-3
3'
AUG
5'
Transcribed Image Text:A IF-3 30S subunit 3' 5' MRNA transcript AUG Shine-Dalgarno Sequence В fMet-TRNA; fMet IF-2- GTP IF-1 3' AUG 5' 50S subunit fMet A GTP AUG fMet GDP + Pi IF-1 IF-2 IF-3 3' AUG 5'
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