Describe the mechanism shown for a double zinc aminopeptidase. The image shows the catalysis pathway of double zinc aminopeptidase Describe the chemistry of each step (what is happening in each step/pathway) How the enzyme appears or might facilitate the chemistry How the enzyme increases the reaction rate..

Chemistry & Chemical Reactivity
9th Edition
ISBN:9781133949640
Author:John C. Kotz, Paul M. Treichel, John Townsend, David Treichel
Publisher:John C. Kotz, Paul M. Treichel, John Townsend, David Treichel
Chapter24: Biochemistry
Section24.3: Nucleic Acids
Problem 1RC: 1. Which breaks down more quickly in an aqueous solution? DNA RNA
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Describe the mechanism shown for a double zinc aminopeptidase. The image shows the catalysis pathway of double zinc aminopeptidase

  • Describe the chemistry of each step (what is happening in each step/pathway)
  • How the enzyme appears or might facilitate the chemistry
  • How the enzyme increases the reaction rate..              
R1
H
(Реp)
R1
(Pep)
H2N
R2
-Glu131
H.
H2N'
R2
Glu131
"OH
но
он
Zn
он Zn
Zn
Tyr246
Tyr246
H2N,
-(Реp)
R1
R1
R2
(Рер)
H2N
-OH
H2N
R2
-Glu131
Glu131
он
Он
он
Zn Zn
Tyr246
Tyr246
H20
Zn
Zn
R1
+H2
-(Pep)
H2N
он
-Glu131
OH Zn Zn
Тyr246
IZ
Transcribed Image Text:R1 H (Реp) R1 (Pep) H2N R2 -Glu131 H. H2N' R2 Glu131 "OH но он Zn он Zn Zn Tyr246 Tyr246 H2N, -(Реp) R1 R1 R2 (Рер) H2N -OH H2N R2 -Glu131 Glu131 он Он он Zn Zn Tyr246 Tyr246 H20 Zn Zn R1 +H2 -(Pep) H2N он -Glu131 OH Zn Zn Тyr246 IZ
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