Q: Explain the role of toxicological parameters ED50 in ensuring the safety of a drug candidate.…
A: Toxicological parameters - It is the level of toxicity to determine drug usage. The toxicological…
Q: What is DPI? What are the advantages of DPI over MDI? How drug is aerosolized from a DPI system?…
A: Inhalers are the devices which delivers the medication to the targeted organ with effective drug…
Q: find stereochemistry, (from the structure) , rotational bond and geometrical / optical isomer for…
A: Phenyotin is a synthetic compound and also called Diphenylhydantoin and it is a potent…
Q: Identify the possible intermolecular forces existing in the structures presented below and justify.…
A: The given drug is doxorubicin. It is also known as Adriamycin and is used as chemotherapy medication…
Q: For each of the following pharmacologic classification of antihypertensive agents, list (a) at least…
A: Medications that treats hypertension or increased levels of blood pressure are known as…
Q: Explain synthetic lethality.
A: Synthetic lethality is a condition which arises when a combination of deficiencies in the expression…
Q: Discuss the various categories of controlled substances, and give specific drug examples in each…
A: Controlled substances: Any type of chemical that has the potential to alter the physical and mental…
Q: Summarize the major physicochemical properties of small molecule drugs and how each of these will…
A: The physicochemical properties of the small drug molecule are associated to elicit the therapeutic…
Q: Discuss the effects of glass packaging materials on pharmaceutical dosage form? Discuss at your own…
A: Packaging refers to the process of wrapping or safeguarding products in preparation for delivery,…
Q: what is pharmacophore? what is the importance of pharmacophore in drug discovery?
A: The drug is the chemical substance that is responsible for altering the function of living things.…
Q: Explain the role of different toxicological parameters (i.e. ED50, TD50, LD50, NOAEL, LOAEL, etc.)…
A: A drug is any substance that can affect psychology or physiology when taken into the body. It is…
Q: Explain mechanisms of drug toxicity? How various strategies are used to treat the drug toxicity and…
A: Drug toxicity can be outlined as the toxicity which occurs because of ingesting more drugs that are…
Q: Using a schematic diagram, illustrate the process of the following stages of drug development:…
A: Stage 1: Discovery and Development:Drug disclosure is the manner by which new prescriptions are…
Q: When two antimicrobial drugs are used at the same time, antagonistic effects can occur. Which of the…
A: When two or more drugs are used together, there happens to be some interactions between the drugs…
Q: How we can improve (potency, selectivity and decrease in toxicity ) for the development of a…
A: Antihistamines are drugs that are used to treat allergic conditions like sneezing, runny nose,…
Q: Explain the relationship between the minimum inhibitory concentrationand the therapeutic index. What…
A: Microorganisms are resistant or susceptible to antimicrobial drugs. It can be determined by drug…
Q: Discuss the difference between first-generation and second-generation antihistamines
A: Antihistamines is a family of drug used for the treatment of allergic reactions. Histamines are…
Q: Can you determine why some drugs have narrower spectra than others?
A: A narrow-spectrum antimicrobial targets only specific subsets of bacterial pathogens. For example,…
Q: Considering the amount of drug information available in the internet, how will you know which one to…
A: Drug information refers to giving therapeutically relevant information on any element of drug usage,…
Q: Why excipients are used in drug formulation? Explain the role of excipients in preparation with…
A: Drug excipients are essentially inactive substances apart from the active ingredients, which are…
Q: what is lead compound ? define lead compound in terms of drug discovery?
A: Drug discovery and development is the process by which a potential drug candidate is identified,…
Q: Explain the uses of the minimum inhibitory concentration and thetherapeutic index in drug selection.
A: Microbes that cause diseases are called pathogens.
Q: what are the purpose of drug metabolism?
A: Drug metabolism is metabolic breakdown of drugs in the body with the help of specific enzymes. It is…
Q: Explain the major mechanisms by which microbes becomeresistant to drugs.
A: Antimicrobial resistance refers to the condition that occurs when microorganisms such as bacteria,…
Q: Explain the term first-pass eject or hepatic metabolism of the drug. What effect does first-pass…
A: Introduction:- Drugs are the form or a type of medicine which are used to treat different types of…
Q: Identify the general categories of the cellular targets of physical and chemical agents.
A: A cell is the basic unit of life that eventually assembles into a whole creature. A cell contains a…
Q: Describe the factors that affect both drug absorption and bioavailability.
A: Drug absorption : The most important principle in pharmacokinetics theory is drug absorption. The…
Q: Define about Sulfa Drugs ?
A: Antibiotics are considered chemical compounds, which are helping to prevent bacterial infections.
Q: describe four modes of action of antimicrobial agents, and give a specific example of how each works
A:
Q: explain how the different targets of antimicrobial drugs work in relation to selective toxicity.
A: Bacteria is a prokaryote that can be found everywhere in this world. Some are harmful and some are…
Q: Enumerate the different sources of drug. Provide example for each source. Discuss the advantages and…
A: Sources of drugs Natural sources Plants Animals Microbes Minerals Artificial sources Synthetic Semi-…
Q: Describe drawbacks associated with the use of topical powder dosage forms, and provide examples of…
A: Powders are dry mixtures of finely split medicinal and non-medicinal ingredients intended for…
Q: Describe three situations where you would use an excipient in your drug formulation and how you…
A: Excipients can be outlined as inert substances that are utilized in the drugs as diluents.…
Q: What is drug stability in pharmacy?
A: It is asked, what is drug stability in pharmacy?
Q: Define the concept of drug bioavailability and briefly explain how it is experimentally determined.…
A: bio-availability of a drug is the indicator or measure to check how much the administered dosage of…
Q: Explain the role of toxicological parameters LOAEL in ensuring the safety of a drug candidate.…
A: In the development of a new drug, it is very important make sure about the safety profile of the…
Q: Name the desirable characteristics of chemical control agents.
A: In most cases, chemical agents aren't designed to sterilise. The majority of the time, pathogens are…
Q: With references added,give a detailed mechanism of action for the drug Entresto.
A: ENTRESTO- ENTRESTO is a combination of two medications: valsartan, a neprilysin inhibitor, and…
Define therapeutic index and explain its importance.
Step by step
Solved in 2 steps
- Describe the significance of the use of pharmacokinetic parameters in case to calculate appropriate drug dosing regimens.What are the potential implications of genetic variations in drug-metabolizing enzymes on individual response and therapeutic outcomes in clinical pharmacology?Describe the factors that affect both drug absorption and bioavailability.
- Identify the classification of drug metabolism and specific type of reaction involved in each drugsample. Identify the enzyme involved in each reaction.Identify the classification of drug metabolism and specific type of reaction involved in each drugsample. Identify the enzyme involved in each reaction.Briefly explain this statement "Preformulation studies help to find the drug performance and the development of a dosage form"-explain this with different drug properties and example? Please answer at your own easy words.