Corticospinal tract review questions 11. The cell bodies of the upper motor neurons originate in the cortex of the gyrus of the lobe. The axons of these neurons descend between the thalamus and cerebral nuclei t form the capsule. The lateral corticospinal tract crosses over in the of the medulla. The axons of the lateral corticospinal tract synapse with the cell bodies of the lower motor neurons in the horn of the spinal cord.

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