Combinations of regulatory proteins control cell types MAT locus a2 at a2 a1 Expressed regulatory proteins a2 a1 a2 MCM1 MCM1 MCM1 a2 a2 a-specific genes ON OFF OFF MCM1 MCM1 MCM1 a1 a-specific genes OFF ON OFF MCM1 a1 a2 Haploid-specific ON ON OFF genes (a) a cell (b) a cell (c) ala cell FIGURE 12-10 Control of cell-type- specific gene expression in yeast. The three cell types of S. cerevisiae are determined by the regulatory proteins a1, a1, and a2, which regulate different subsets of target genes. The MCM1 protein acts in all three cell types and interacts with a1 and o2. In a diploid yeast cell, regulatory proteins encoded by each MAT locus are expressed (Figure 12-10c). What is the result? All the structural genes involved in cell mating are shut down, as are a separate set of genes, called haploid specific, that are expressed in haploid cells but not diploid cells. How does this happen? The a1 protein encoded by MAT has a part to play at last. The a1 protein can bind to some of the o2 protein present and alter its binding specificity such that the al-a2 com-
Combinations of regulatory proteins control cell types MAT locus a2 at a2 a1 Expressed regulatory proteins a2 a1 a2 MCM1 MCM1 MCM1 a2 a2 a-specific genes ON OFF OFF MCM1 MCM1 MCM1 a1 a-specific genes OFF ON OFF MCM1 a1 a2 Haploid-specific ON ON OFF genes (a) a cell (b) a cell (c) ala cell FIGURE 12-10 Control of cell-type- specific gene expression in yeast. The three cell types of S. cerevisiae are determined by the regulatory proteins a1, a1, and a2, which regulate different subsets of target genes. The MCM1 protein acts in all three cell types and interacts with a1 and o2. In a diploid yeast cell, regulatory proteins encoded by each MAT locus are expressed (Figure 12-10c). What is the result? All the structural genes involved in cell mating are shut down, as are a separate set of genes, called haploid specific, that are expressed in haploid cells but not diploid cells. How does this happen? The a1 protein encoded by MAT has a part to play at last. The a1 protein can bind to some of the o2 protein present and alter its binding specificity such that the al-a2 com-
Biology: The Dynamic Science (MindTap Course List)
4th Edition
ISBN:9781305389892
Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Chapter9: Cell Communication
Section: Chapter Questions
Problem 2ITD
Related questions
Question
Contrast the role of the MCM1 protein in different yeast
cell types shown in Figure 12-10. How are the a-specific
genes controlled differently in different cell types?
Expert Solution
This question has been solved!
Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.
Step by step
Solved in 2 steps
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Recommended textbooks for you
Biology: The Dynamic Science (MindTap Course List)
Biology
ISBN:
9781305389892
Author:
Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher:
Cengage Learning
Biology 2e
Biology
ISBN:
9781947172517
Author:
Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:
OpenStax
Biology: The Dynamic Science (MindTap Course List)
Biology
ISBN:
9781305389892
Author:
Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher:
Cengage Learning
Biology 2e
Biology
ISBN:
9781947172517
Author:
Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:
OpenStax