Cellular reprogramming and induced pluripotent stem cells have allowed scientists to model various diseases and screen drugs in these in vitro models. Question: A drug that has been screened in cancer model through the generation of induced pluripotent stem cells. Please explain in detail the main findings

Cellular reprogramming and induced pluripotent stem cells have allowed scientists to model various diseases and screen drugs in these in vitro models. Question: A drug that has been screened in cancer model through the generation of induced pluripotent stem cells. Please explain in detail the main findings

Biomedical Instrumentation Systems

1st Edition

ISBN:9781133478294

Author:Chatterjee

Publisher:Chatterjee

Chapter24: New Technologies And Advances In Medical Instrumentation

Section: Chapter Questions

Problem 4P

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Cellular reprogramming and induced pluripotent stem cells have allowed scientists to model various diseases and screen drugs in these in vitro models. Cancer is modeled through the generation of induced pluripotent stem cells. Please explain the questions in detail (Especially 2nd and 3rd question please, thank you):1) why is it important to model such a disease(cancer)?2) what were the key findings after modeling such a disease (cancer)? 3) a drug that has been screened in this disease model (cancer). Explain in detail the main findings.
Cellular reprogramming and induced pluripotent stem cells have allowed scientists to model various diseases and screen drugs in these in vitro models. Please select a disease (like cancer) that can be modeled through the generation of induced pluripotent stem cells. You can use published literature and explain:1) why is it important to model such a disease?2) what were the key findings after modeling such a disease? 3) a drug that has been screened in this disease model. Explain in detail the main findings.
A drug that has been screened in cancer model through the generation of induced pluripotent stem cells. Explain in detail the main findings.
Cellular reprogramming and induced pluripotent stem cells have allowed scientists to model various diseases and screen drugs in these in vitro models. Please select a disease that can be modeled through the generation of induced pluripotent stem cells. What were the key findings after modeling such a disease? Please explain clearly with example Thank you
Why is it important to model cancer through the generation of induced pluripotent stem cells ? Explain in detail the main findings.
Why is it important to model cancer through the generation of induced pluripotent stem cells ? Explain in detail the main findings. Please sort as a list.
Cellular reprogramming and induced pluripotent stem cells have allowed scientists to model various diseases and screen drugs in these in vitro models. Please select a disease that can be modeled through the generation of induced pluripotent stem cells. 1) a drug that has been screened in this disease model. Explain in detail the main findings.
Why is it important to model cancer through the generation of induced pluripotent stem cells ? Please list item by item. Explain in detail the main findings.
Why is it important to model cancer through the generation of induced pluripotent stem cells ? Please explain in details
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For many years, targeted therapies for cancer treatment continue to be developed, however more and more patients are developing resistance to targeted therapies. Discuss one mechanism of resistance to targeted therapies for cancer and provide an example of how might creatively combat it using clinical concepts.
Cancer stem cells (CSCs) are cancer cells (found within tumors or hematological cancers) that possess characteristics associated with normal stem cells, specifically the ability to give rise to all cell types found in a particular cancer sample. There are many biomedical engineering based approaches to detect CSCs. Question: What kind of systems have been developed to detect CSCs? Describe by giving examples. Please explain with a few examples.