Cell Line Mutation WT none (wild type DNA) 1 a deletion at the same region on both copies of chromosome 4 2 a point mutation in a gene on only one copy of chromosome 7 You learn that cell line 2 is a breast cancer cell line that expresses a mutant version of a receptor protein called KIT. Based on this data, which of the following is true ? Select all that apply Activation of KIT promotes progression through the cell cycle Activation of KIT releases an inhibition of a cyclin Activation of KIT causes cells to enter GO Activation of KIT promotes cells to undergo apoptosis
Cell Line Mutation WT none (wild type DNA) 1 a deletion at the same region on both copies of chromosome 4 2 a point mutation in a gene on only one copy of chromosome 7 You learn that cell line 2 is a breast cancer cell line that expresses a mutant version of a receptor protein called KIT. Based on this data, which of the following is true ? Select all that apply Activation of KIT promotes progression through the cell cycle Activation of KIT releases an inhibition of a cyclin Activation of KIT causes cells to enter GO Activation of KIT promotes cells to undergo apoptosis
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Transcribed Image Text:Your friend sends you two cancerous cell lines to examine and determine possible mutations.
The results are shown below:
Cell Line
Mutation
WT
none (wild type DNA)
1
a deletion at the same region on both copies of chromosome 4
a point mutation in a gene on only one copy of chromosome 7
You learn that cell line 2 is a breast cancer cell line that expresses a mutant version of a receptor protein called KIT.
Based on this data, which of the following is true ? Select all that apply
Activation of KIT promotes progression through the cell cycle
V Activation of KIT releases an inhibition of a cyclin
Activation of KIT causes cells to enter GO
V Activation of KIT promotes cells to undergo apoptosis
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