Below is the summary of the Tuskegee Syphilis Study.  What sorts of ethical problems does this study present?      Tuskegee syphilis study, it’s official name is “Tuskegee Study of Untreated Syphilis in the Negro Male”. It’s an American medical research project that earned notoriety for its unethical experimentation on African American patients in the rural South. The project was conducted by the U.S. Public Health Service from 1932 to 1972 to examine the natural course of untreated syphilis in African American men.  The research was intended to test whether syphilis caused cardiovascular damage more often than neurological damage and to determine if the natural course of syphilis in black men was significantly different from that in whites.  To recruit participants for its study, the PHS enlisted the support of the prestigious Tuskegee Institute (now Tuskegee University), located in Macon County, Alabama. A group of 399 infected patients and 201 uninfected control patients were recruited for the program. The subjects were all impoverished sharecroppers from Macon county. The original study was scheduled to last only six to nine months. The subjects were not told that they had syphilis or that the disease could be transmitted through sexual intercourse. Instead, they were told that they suffered from "bad blood," a local term used to refer to a range of diseases. Treatment was initially part of the study, and some patients were administered arsenic, bismuth, and mercury. But after the original study failed to produce any useful data, it was decided to follow the subjects until their deaths, and all treatment was halted. Penicillin was denied to the infected men after that drug became available in the mid-1940s, and it was still being withheld from them 25 years later, in direct violation of government legislation that mandated the treatment of venereal disease. It is estimated that more than 100 of the subjects died of tertiary syphilis.

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Chapter16: Antifungal, Antiviral, And Immunizing Agents
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 Below is the summary of the Tuskegee Syphilis Study.  What sorts of ethical problems does this study present? 

 

 

Tuskegee syphilis study, it’s official name is “Tuskegee Study of Untreated Syphilis in the Negro Male”. It’s an American medical research project that earned notoriety for its unethical experimentation on African American patients in the rural South. The project was conducted by the U.S. Public Health Service from 1932 to 1972 to examine the natural course of untreated syphilis in African American men. 

The research was intended to test whether syphilis caused cardiovascular damage more often than neurological damage and to determine if the natural course of syphilis in black men was significantly different from that in whites. 

To recruit participants for its study, the PHS enlisted the support of the prestigious Tuskegee Institute (now Tuskegee University), located in Macon County, Alabama. A group of 399 infected patients and 201 uninfected control patients were recruited for the program. The subjects were all impoverished sharecroppers from Macon county. The original study was scheduled to last only six to nine months.

The subjects were not told that they had syphilis or that the disease could be transmitted through sexual intercourse. Instead, they were told that they suffered from "bad blood," a local term used to refer to a range of diseases. Treatment was initially part of the study, and some patients were administered arsenic, bismuth, and mercury. But after the original study failed to produce any useful data, it was decided to follow the subjects until their deaths, and all treatment was halted. Penicillin was denied to the infected men after that drug became available in the mid-1940s, and it was still being withheld from them 25 years later, in direct violation of government legislation that mandated the treatment of venereal disease. It is estimated that more than 100 of the subjects died of tertiary syphilis.

 

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