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- Explain the term first-pass eject or hepatic metabolism of the drug. What effect does first-pass have on drug bioavailability and activity?What is more preferred for drug therapy, conventional or modified release dosage forms? Please provide informations that would support the claim.What are the potential implications of genetic variations in drug-metabolizing enzymes on individual response and therapeutic outcomes in clinical pharmacology?
- Briefly explain this statement -"Therapeutic drug monitoring of Warfarin" Please explain at your own words(500-600 words appropriately).Discuss three types of drug-drug interactions, and explain the links to pharmacodynamics and/or pharmacokinetics, with examples. Give the mechanims.Briefly explain the therapeutic drug monitoring of Warfarin? Please explain at your own words.
- Please give these information for this drug named Atogepant. 1) Indications 2) Usage 3) Dosages and Administration 4) Contraindication 5) Use in specific population 6) Dosage form and Strength. Please shortly answer at your own easy words. Answer should be to the point.How can you identify a rational prescription? Please shortly answer at your own easy words. Answer should be to the point.For quinidine List the major adverse drug-drug interactions and drug-food interactions that clients need to be made aware of.
