As a pharmacological researcher, you are tasked discover a drug for a neurodegenerative disease that caused by protein-misfolding. The protein- misfolding results in secretion of three or more enzymes with similar active sites but different allosteric sites. Those misfolded enzymes are wrecking havoc in the bodily functions. You understand the key to the cure of this disease is by disabling the misfolded enzymes. of enzyme Based on the knowledge of enzymatic activities, identify the type inhibitors that be used as a drug. Explain the mechanism of disabling the misfolded enzymes with the aids of a hand drawn diagram.

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Mitochondrial Mutations

A mitochondrion is a cellular organelle that serves as the site for cellular respiration and energy production (ATP or Adenosine Triphosphate). It is a double-membrane-bound organelle and is only present in eukaryotic cells.