Acyl transfer (nucleophilic substitution at carbonyl)reactions proceed in two stages via a "tetrahedralintermediate." Draw the tetrahedral intermediate as it isfirst formed in the following reaction.CIH₂NOH• You do not have to consider stereochemistry.• Include all valence lone pairs in your answer.• Do not include counter-ions, e.g., Na+, I, in youranswer.• In cases where there is more than one answer,just draw one.Sn [F

H2NCH2CH2OH have two nucleophilic centers. One is N center and another is O center. N is less…

Acyl transfer (nucleophilic substitution at carbonyl) reactions proceed in two stages via a "tetrahedral intermediate." Draw the tetrahedral intermediate as it is first formed in the following reaction. H₂N OH

Acyl transfer (nucleophilic substitution at carbonyl) reactions proceed in two stages via a "tetrahedral intermediate." Draw the tetrahedral intermediate as it is first formed in the following reaction. H₂N OH

Organic Chemistry: A Guided Inquiry

2nd Edition

ISBN:9780618974122

Author:Andrei Straumanis

Publisher:Andrei Straumanis

Chapter20: Acidity And Pka Of Phenols

Section: Chapter Questions

Problem 11E

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Concept explainers

Diol

In chemistry there are so many chemical compounds that have a hydroxyl group but a chemical compound having two hydroxyl groups (-OH) is termed as a diol. It also implies the presence of two alcohols whereas polyols contain two or more than two hydroxyl groups (-OH). Glycol or 1,2-diol is an aliphatic diol that has two alcohol groups on adjacent carbon atoms. In industries, the most commonly used diol is ethylene glycol.

Question

Acyl transfer (nucleophilic substitution at carbonyl)
reactions proceed in two stages via a "tetrahedral
intermediate." Draw the tetrahedral intermediate as it is
first formed in the following reaction.
CI
H₂N
OH
• You do not have to consider stereochemistry.
• Include all valence lone pairs in your answer.
• Do not include counter-ions, e.g., Na+, I, in your
answer.
• In cases where there is more than one answer,
just draw one.
Sn [F

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