A new supplement, "A” has been introduced as a potential intervention to reduce the risk of osteoporotic fractures in postmenopausal women. A randomized controlled trial was conducted to assess the efficacy of “A” compared to a placebo in preventing osteoporotic fractures. In the trial, 800 postmenopausal women were randomly assigned to two groups. Group A received "A”, while Group B received a placebo. After two years of supplementation, the occurrence of osteoporotic fractures was recorded. In Group A, 30 women experienced osteoporotic fractures, while in Group B, 10 women had similar events. Calculate the relative risk of experiencing an osteoporotic fracture for postmenopausal women in Group A "A” compared to Group B (placebo). Use the provided data: 30 osteoporotic fractures in Group A and 10 in Group B? Interpret the calculated relative risk & Discuss the implications of this result on the potential effectiveness and safety of "A” in reducing the risk of osteoporotic fractures in postmenopausal women?

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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A new supplement, "A” has been introduced as a potential intervention to reduce the risk of osteoporotic fractures in postmenopausal women. A randomized controlled trial was conducted to assess the efficacy of “A” compared to a placebo in preventing osteoporotic fractures.

In the trial, 800 postmenopausal women were randomly assigned to two groups. Group A received "A”, while Group B received a placebo. After two years of supplementation, the occurrence of osteoporotic fractures was recorded. In Group A, 30 women experienced osteoporotic fractures, while in Group B, 10 women had similar events.

  1. Calculate the relative risk of experiencing an osteoporotic fracture for postmenopausal women in Group A "A” compared to Group B (placebo). Use the provided data: 30 osteoporotic fractures in Group A and 10 in Group B?
  2. Interpret the calculated relative risk & Discuss the implications of this result on the potential effectiveness and safety of "A” in reducing the risk of osteoporotic fractures in postmenopausal women?
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