A member of the landing party has been sent to sickbay after being exposed to high levels of carbon monoxide. In order for Dr. McCoy to treat this patient he needs to know the degree of poisoning that has occurred. He will first explain to you why the carbon monoxide is a poison and then tell you what information he needs, please help him: The hemoglobin molecule carries O, in the blood from the lungs to the cells, where the O, is released for metabolic processes. The molecule can be represented as Hb in its unoxygenated form and as Hb O2 in its oxygenated form. One reason CO is toxic is that it competes with O2 for binding to Hb: Hb Oz(aq) + CO Hb CO(ag) + O2(aq) A G° =-14 kJ at 37°C (body temperature) What is the ratio of [Hb CO/[Hb O2] at 37 °C with [O2] = [CO]?

Chemistry & Chemical Reactivity
10th Edition
ISBN:9781337399074
Author:John C. Kotz, Paul M. Treichel, John Townsend, David Treichel
Publisher:John C. Kotz, Paul M. Treichel, John Townsend, David Treichel
Chapter18: Principles Of Chemical Reactivity: Entropy And Free Energy
Section18.7: The Interplay Of Kinetics And Thermodynamics
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A member of the landing party has been sent to sickbay after being exposed to high levels of
carbon monoxide. In order for Dr. McCoy to treat this patient he needs to know the degree of
poisoning that has occurred. He will first explain to you why the carbon monoxide is a poison and
then tell you what information he needs, please help him:
The hemoglobin molecule carries O, in the blood from the lungs to the cells, where the O, is
released for metabolic processes. The molecule can be represented as Hb in its unoxygenated
form and as Hb O2 in its oxygenated form. One reason CO is toxic is that it competes with O, for
binding to Hb:
Hb O2(aq) + CO Hb CO(aq) +
A G° = -14 kJ at 37°C (body temperature)
What is the ratio of [Hb CO/[HbO2] at 37 °C with [O2] = [CO]?
Transcribed Image Text:A member of the landing party has been sent to sickbay after being exposed to high levels of carbon monoxide. In order for Dr. McCoy to treat this patient he needs to know the degree of poisoning that has occurred. He will first explain to you why the carbon monoxide is a poison and then tell you what information he needs, please help him: The hemoglobin molecule carries O, in the blood from the lungs to the cells, where the O, is released for metabolic processes. The molecule can be represented as Hb in its unoxygenated form and as Hb O2 in its oxygenated form. One reason CO is toxic is that it competes with O, for binding to Hb: Hb O2(aq) + CO Hb CO(aq) + A G° = -14 kJ at 37°C (body temperature) What is the ratio of [Hb CO/[HbO2] at 37 °C with [O2] = [CO]?
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