A compound is known to have a free amino group with a pKa of 8.8, and one other ionizable group with a pKa between 5 and 7. To 100 mL of a 0.2 M solution of this compound at pH 8.2 was added 40 mL of a solution of 0.2 M hydrochloric acid. The pH changed to 6.2. The pKa of the second ionizable group is?

Organic Chemistry
9th Edition
ISBN:9781305080485
Author:John E. McMurry
Publisher:John E. McMurry
Chapter26: Biomolecules: Amino Acids, Peptides, And Proteins
Section26.SE: Something Extra
Problem 34AP: Using both three- and one-letter codes for amino acids, write the structures of all possible...
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A compound is known to have a free amino group with a pKa of 8.8, and one other
ionizable group with a pKa between 5 and 7. To 100 mL of a 0.2 M solution of this
compound at pH 8.2 was added 40 mL of a solution of 0.2 M hydrochloric acid. The pH
changed to 6.2. The pKa of the second ionizable group is?
Transcribed Image Text:A compound is known to have a free amino group with a pKa of 8.8, and one other ionizable group with a pKa between 5 and 7. To 100 mL of a 0.2 M solution of this compound at pH 8.2 was added 40 mL of a solution of 0.2 M hydrochloric acid. The pH changed to 6.2. The pKa of the second ionizable group is?
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