(A) 오모오후 인모오모 오모오모 민오모후 (B) 오모오후 Figure Q7-3 Pedigrees reflecting matemal and paternal imprinting (Problem 7-12). In one pedigree, the gene is patemally imprinted; in the other, it is maternally imprinted. In generations 3 and 4, only one of the two parents in the indicated matings is shown; the other parent is a normal individual from outside this pedigree. Affected individuals are represented by red circles for females and red squares for males. Dotted yellow symbols indicate individuals that carry the deletion but do not display the phenotype.

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Examine the two pedigrees shown in Figure Q7–3.
One results from deletion of a maternally imprinted auto-
somal gene. The other pedigree results from deletion of a
paternally imprinted autosomal gene. In both pedigrees,
affected individuals (red symbols) are heterozygous for
the deletion. These individuals are affected because one
copy of the chromosome carries an imprinted, inactive
gene, while the other carries a deletion of the gene. Dotted
yellow symbols indicate individuals that carry the deleted
locus, but do not display the mutant phenotype. Which
pedigree is based on paternal imprinting and which on
maternal imprinting? Explain your answer.

(A)
오모오후
인모오모 오모오모 민오모후
(B)
오모오후
Figure Q7-3 Pedigrees reflecting matemal and paternal imprinting
(Problem 7-12). In one pedigree, the gene is patemally imprinted; in
the other, it is maternally imprinted. In generations 3 and 4, only one
of the two parents in the indicated matings is shown; the other parent
is a normal individual from outside this pedigree. Affected individuals
are represented by red circles for females and red squares for males.
Dotted yellow symbols indicate individuals that carry the deletion but
do not display the phenotype.
Transcribed Image Text:(A) 오모오후 인모오모 오모오모 민오모후 (B) 오모오후 Figure Q7-3 Pedigrees reflecting matemal and paternal imprinting (Problem 7-12). In one pedigree, the gene is patemally imprinted; in the other, it is maternally imprinted. In generations 3 and 4, only one of the two parents in the indicated matings is shown; the other parent is a normal individual from outside this pedigree. Affected individuals are represented by red circles for females and red squares for males. Dotted yellow symbols indicate individuals that carry the deletion but do not display the phenotype.
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