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A 36-year-old man named Michael Ang was brought into the emergency room with complaints of coughing, jaundice, exhaustion, and dizziness. He also displayed symptoms of anemia. He was noted to have "alcohol smell" upon admission. Hepatomegaly and splenomegaly are both present. ● His Blood examination revealed: O MCV 75/fL and Hemoglobin 110 g/L. Serum Iron and Ferritin: Increased. Total Iron binding capacity: Normal. O Transferrin saturation: High Platelet and leukocyte level: Normal Blood smear analysis: Anisocytosis, Poikilocytosis and iron containing inclusions are present. Bone marrow aspirate smear: Presence of sideroblasts. O O O O O 1. Based on the initial findings, what is the possible hematologic disorder / illness of the patient? Support your answer. 2. What are the possible causes of this condition? 3. What additional test/s are useful for the Patient's condition? 4. Discuss the pathophysiology of the condition.

A 36-year-old man named Michael Ang was brought into the emergency room with complaints of coughing, jaundice, exhaustion, and dizziness. He also displayed symptoms of anemia. He was noted to have "alcohol smell" upon admission. Hepatomegaly and splenomegaly are both present. ● His Blood examination revealed: O MCV 75/fL and Hemoglobin 110 g/L. Serum Iron and Ferritin: Increased. Total Iron binding capacity: Normal. O Transferrin saturation: High Platelet and leukocyte level: Normal Blood smear analysis: Anisocytosis, Poikilocytosis and iron containing inclusions are present. Bone marrow aspirate smear: Presence of sideroblasts. O O O O O 1. Based on the initial findings, what is the possible hematologic disorder / illness of the patient? Support your answer. 2. What are the possible causes of this condition? 3. What additional test/s are useful for the Patient's condition? 4. Discuss the pathophysiology of the condition.

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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A 36-year-old man named Michael Ang was brought into the emergency room with complaints of coughing, jaundice, exhaustion, and dizziness. He also displayed symptoms of anemia. He was noted to have "alcohol smell" upon admission. Hepatomegaly and splenomegaly are both present. ● His Blood examination revealed: O MCV 75/fL and Hemoglobin 110 g/L. Serum Iron and Ferritin: Increased. Total Iron binding capacity: Normal. Transferrin saturation: High Platelet and leukocyte level: Normal Blood smear analysis: Anisocytosis, Poikilocytosis and iron containing inclusions are present. Bone marrow aspirate smear: Presence of sideroblasts. O O 1. Based on the initial findings, what is the possible hematologic disorder / illness of the patient? Support your answer. 2. What are the possible causes of this condition? 3. What additional test/s are useful for the Patient's condition? 4. Discuss the pathophysiology of the condition.
Transcribed Image Text:A 36-year-old man named Michael Ang was brought into the emergency room with complaints of coughing, jaundice, exhaustion, and dizziness. He also displayed symptoms of anemia. He was noted to have "alcohol smell" upon admission. Hepatomegaly and splenomegaly are both present. ● His Blood examination revealed: O MCV 75/fL and Hemoglobin 110 g/L. Serum Iron and Ferritin: Increased. Total Iron binding capacity: Normal. Transferrin saturation: High Platelet and leukocyte level: Normal Blood smear analysis: Anisocytosis, Poikilocytosis and iron containing inclusions are present. Bone marrow aspirate smear: Presence of sideroblasts. O O 1. Based on the initial findings, what is the possible hematologic disorder / illness of the patient? Support your answer. 2. What are the possible causes of this condition? 3. What additional test/s are useful for the Patient's condition? 4. Discuss the pathophysiology of the condition.
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