80. An investigator is studying the effects of a hormone in two groups of experimental animals. During a 2-hour period, Group X receives an infusion of 0.9% saline and Group Y receives an infusion of the hormone. The following findings are recorded: Pulse Mean arterial blood pressure Serum OF) Growth hormone G) Thyroxine (T4) Group Y most likely received which of the following hormones? OA) ADH (vasopressin) B) Aldosterone C) Cortisol OD) Epinephrine E) Glucagon Glucose Free fatty acids Plasma renin Group X 380/min 120 mm Hg 80 mg/dL 3.5 μEq/L 2.5 ng/ml/h Group Y 550/min 150 mm Hg 130 mg/dl. 7.5 pEq/L 18 ng/mL/h
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- 80. An investigator is studying the effects of a hormone in two groups of experimental animals. During a 2-hour period, Group X receives an infusion of 0.9% saline and Group Y receives an infusion of the hormone. The following findings are recorded: Customized Subject Test Pulse Mean arterial blood pressure Serum Glucose Free fatty acids Plasma renin Group Y most likely received which of the following hormones? A) ADH (vasopressin) B) Aldosterone C) Cortisol D) Epinephrine E) Glucagon F) Growth hormone G) Thyroxine (T4) Group X 380/min 120 mm Hg 80 mg/dL 3.5 µEq/L 2.5 ng/mL/h Group Y 550/min 150 mm Hg 130 mg/dL 7.5 mEq/L 18 ng/mL/h80. An investigator is studying the effects of a hormone in two groups of experimental animals. During a 2-hour period, Group X receives an infusion of 0.9% saline and Group Y receives an infusion of the hormone. The following findings are recorded: Group X Group Y Pulse 380/min 550/min Mean arterial blood pressure Serum 120 mm Hg 150 mm Hg Glucose 80 mg/dL 130 mg/dL Free fatty acids 3.5 JEq/L 7.5 JEq/L Plasma renin 2.5 ng/ml/h 18 ng/mL/h Group Y most likely received which of the following hormones? A) ADH (vasopressin) B ) Aldosterone C ) Cortisol D) Epinephrine E) Glucagon F) Growth hormone G) Thyroxine (T 4)Write down the mode of action of Rosuvastatin and Fenofibrates? Please explain at your own words .
- In a breast cancer patient whose tumor cells express large amounts of estrogen receptors and are therefore very sensitive to estradiol, which of these drugs will be very effective in reducing plasma levels of estradiol and consequently the breast tumor growth? Group of answer choices Letrozole Paclitaxel Methotrexate MegestrolA 30-year-old female patient with uncontrolled hypertension is suspected by an investi- gating endocrinologist of having Conn's syndrome. Results of routine biochemistry were (reference ranges are given in brackets): Sodium Potassium Urea Creatinine Alkaline phosphatase Alanine aminotransferase Albumin Bilirubin Calcium 146 mmol/L 2.1 mmol/L 7.2 mmol/L 146 μmol/L 290 IU/L 20 IU/L 49 g/L 8 μmol/L 2.19 mmol/L (135-145) (3.5-5.0) (3.5-6.6) (70-150) (95-320) (5-42) (35-50) (<17) (2.12-2.62) (a) Are any of the electrolyte concentrations abnormal, and if so what condition is suggested? (b) What further biochemistry investigations would you undertake? Explain your reasoning.33) A 30-year-old woman is found to have a low serum FT3 and FT4 level, high serum TSH level after being evaluated for fatigue. Five years ago she had been treated for Graves disease with radioactive iodine. Which option is proper for this patient()? A beta blocker B radioactive iodine C levothyroxine D Aspirin E alpha blocker
- Asare's Laboratory result showed increase in BP, Plasma volume, hypernatremia, hypokalemia and serum renin low. a. What disorder are we talking about here. b. What other hormone or molecule can be use as a therapy.In a diagnostic examination of a patient’s thyroid, the patient, who weights 70 kg, is given a capsule containing 10 micro Ci 131I. Thirty percent of the radioiodine is rapidly taken up by the thyroid, whose weight is estimated as 30 g. Given that 1) the biological half-life of iodine in the thyroid is 120 days, 2) the radiological half-life 131I is 8 days, and 3) the average absorbed energy in the thyroid is 0.21 MeV per disintegration, calculate the a) effective half-life of the radioiodine in the thyroid, in days, b) effective turnover rate of the radioiodine in the thyroid, in percent day-1, c) mean residence time of the radioiodine in the thyroid, in days, d) time for 90% of the radioiodine to be cleared from the thyroid, and e) committed dose to the thyroid, in cGyThese are the questions: What is the weight of epinephrine (in grams) required to make the prescription? What is the volume of water (in milliliters) needed to make the preparation isotonic?
- Hydrocortisone is an over-the-counter ointment commonly used to treat eczema. Eczema is a skin condition where a patch of skin becomes irritated and inflamed. It is estimated that approximately 15% of Canadians are affected by eczema at some point in their lives. The active ingredient in hydrocortisone cream is the hormone cortisol. Which of the following statements describes why hydrocortisone is an effective treatment for eczema? Select one: a. Hydrocortisone helps to fight off the skin infection by increasing the immune response. b. Hydrocortisone helps to suppress the skin inflammation by decreasing the immune response. c. Hydrocortisone helps to suppress the skin inflammation by increasing the immune response. d. Hydrocortisone helps to fight off the skin infection by decreasing the immune response.A 10-week-old child suffered from a salt-wasting crisis. His adrenal glands were enlarged and other organs were normal size. The child is phenotypically female, karotyping showed that the child is 46XY. The biochemical profile shows as: - sodium of 109 (reference range: 134-147) - potassium of 6.1 (reference range: 3.5-5.0) - pregnenlone of 0.002 (reference range: 0.3-1.5) - renin activity of 38 (reference range: 0.5-3.5) - 17-OH pregnenolone of 0.01 (reference range: 6.8-93.5) - ACTH of 1960 (reference range: 0.5-3.5) The cholesterol esters in the adrenal glands accumulated and the concentration of ∆4-androstenedione was not detectable. Also, the enzymes in the steroid biosynthesis did not have detrimental mutations. The child was given treatment with glucocorticoid and mineralocorticoid. Question: a) Which protein is deficient in this case and explain the rationale.Figure 2 shows the results of an oral glucose tolerance test (OGTT) from normal individual. The renal threshold for glucose is 10mM. Figure 2. Change in glucose concentration from an OGTT of a normal individual. a) Draw a similar graph to show how glucose concentration changes in an OGTT from an individual with diabetes. (3 marks) b) What are the 3 key differences in the graph you have drawn that make this a diabetic response? (3 marks)