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- A 24-year-old female has just delivered a baby and will receive 1.9 grams/hr of magnesium sulfate for eclampsia. How many mEq of magnesium sulfate (MW 120; valence 2) will the patient receive in 24 hours?25. ATROVENT Nasal Spray contains 0.03% of ipratropium bromide in a 30-mL me- tered dose container. If the container is calibrated to deliver 345 sprays, calculate the volume of each spray, in microliters, and the medication content of each spray, in micrograms. 25. 86.96 µL /spray and 26.09 µg ipra- tropiumRadiation a) During a workday a worker was discovered to have consumed 1/3 gallon of water contaminated with 2.5 kBq/liter of I-131. Estimate the committed effective dose equivalent (whole body) and organ (thyroid) dose to a reference person. For the whole body dose, calculate in two ways using dose conversion factors and also in relation to the ALI. Show your work. b) An investigation revealed that a worker unknowingly ingested Polonium 210 (form Y). A 24 hour fecal sample measured three months after ingestion contained 5.4 µCi Po- 210. Estimate the committed effective dose equivalent to a reference person.
- Estimate the new dose and dosing interval for morphine, a high extraction ratio drug in a patient with a Child-Pugh score of 8 if the drug is normally given at a dose of 30 mg every 8 hours. A) 7.5 mg every 8 hours B) 22.5 mg every 8 hours C) 30 mg every 6 hours D) 30 mg every 12 hoursA patient received a single 245.97 mg IV bolus dose of an antibiotic and the plasma drug concentration was determined as 13.62 mg/L and 5.94 mg/L at 2.04 hours and 11.52 hours following the drug administration, respectively. On a separate occasion, a single 427.73 mg oral dose of the same antibiotic was administered to the same patient and the plasma drug concentration was determined as 0, 5.01, 5.77, 3.43, 1.1 mg/L at 0, 3.15, 7.69, 14.39, and 27.5 hours following the drug administration. Please calculate the bioavailability of this drug without utilizing any data fitting program.The drug dosage for the patient is calculated using a BSA of 1.9m2. If the order is 15mg per m2, how many milligrams is the desired dose?
- Using conversion factors, solve each of the following clinicalproblems:a. A nurse practitioner prepares an injection of promethazine,an antihistamine used to treat allergic rhinitis. If thestock bottle is labeled 25 mg /mL and the order is a doseof 12.5 mg, how many milliliters will the nurse draw up inthe syringe?b. You are to give ampicillin 25 mg/kg to a child with a massof 62 lb. If stock on hand is 250 mg /capsule, how manycapsules should be given?An intravenous bolus dose of 500 mg Cefotaxime is given to a patient. Drug concentration after 2 and 6 hours of drug administration is 2.5 ug/ml and 0.39 ug/ml respectively. What is volume of distribution? а. 103 b. 25 с. 67 d. 80Give the OSHA standard(s) the CPL applies to (ex: 1926.59).
- A patient takes Mucogel suspension at a daily dose of 10 mL t.i.d. and hs. How much magnesium hydroxide will Mrs A have taken after 5 days of compliant use of Mucogel? (Mucogel contains magnesium hydroxide 195 mg and dried aluminium hydroxide 220 mg/5 mL.)Given the DDF (Density Displacement factor) for morphine HCI is 1.6, calculate the quantity of cocoa butter needed to prepare the following: Morphine HCI: 100mg Cocoa butter: Q.S Quantity of suppositories to make: #7The physician of patient AJ (50 kg, M) admitted in your hospital ordered that the patient receives 0.25 mL of drug A per kg of body weight. This must be mixed with 250 mL of D5W. The IV admixture must be administered over a six-hour period only using a drip set capable of delivering 15 drops per mL. Your pharmacy has stocks of 2.0% w/v of drug A solution (density of drug A: 1.2 g/mL). Answer all questions below. 1. How many mL of drug A must the patient receive to obtain the needed dose? A. 12.5 mL B. 25.0 mL C. 50.0 mL D. 75 mL 2. From the pharmacy's stocks of drug A solution, how many mL must be added to 250 mL D5W to prepare the IV admixture? A. 250 mL B. 500 mL C. 750 mL D. 1000 mL 3. What is the total volume of the admixture that will be administered to the patient? A. 262.50 mL B. 500 mL C. 750 mL D. 1000 mL 4. Given the capability of the hospital's IV set, how many drops of the admixture should be administered to the patient? A. 3,936.5 drops B. 7,500 drops C. 11,250 drops D.…