5 Ethanal, CH₂CHO, can be converted by a two-step synthesis into 2-hydroxypropanoic acid. OH O H₂C- H O H 2-hydroxypropanoic acid (1) The reagents and conditions are 1st step 2nd step NaOH(aq), heat under reflux A Na₂Cr₂O, and dilute H₂SO4 heat under reflux B Cl₂, UV light NaOH(aq), heat und reflux CLIAIH in dry ether CO₂, room temperature D HCN, in presence of KCN(aq) dilute HCl(aq), heat under reflux

Organic Chemistry
9th Edition
ISBN:9781305080485
Author:John E. McMurry
Publisher:John E. McMurry
Chapter22: Carbonyl Alpha-substitution Reactions
Section22.SE: Something Extra
Problem 64AP: The key step in a reported laboratory synthesis of sativene, a hydrocarbon isolated from the mold...
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5 Ethanal, CH₂CHO, can be converted by a two-step synthesis into 2-hydroxypropanoic acid.
OH
O
H₂C-
H
O-H
2-hydroxypropanoic acid
(1)
The reagents and conditions are
1st step
2nd step
NaOH(aq), heat under reflux
A Na₂Cr₂O, and dilute H₂SO4
heat under reflux
B Cl₂, UV light
NaOH(aq), heat und reflux
CLIAIH in dry ether
CO₂, room temperature
D HCN, in presence of KCN(aq)
dilute HCl(aq), heat under reflux
Transcribed Image Text:5 Ethanal, CH₂CHO, can be converted by a two-step synthesis into 2-hydroxypropanoic acid. OH O H₂C- H O-H 2-hydroxypropanoic acid (1) The reagents and conditions are 1st step 2nd step NaOH(aq), heat under reflux A Na₂Cr₂O, and dilute H₂SO4 heat under reflux B Cl₂, UV light NaOH(aq), heat und reflux CLIAIH in dry ether CO₂, room temperature D HCN, in presence of KCN(aq) dilute HCl(aq), heat under reflux
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