3. Using 2-methyloxirane and 2-bromopropane as your only sources of carbon, show how you would synthesize 4-methyl-2-pentanone. Show all reagents and conditions and synthetic intermediates, but you do not need to draw any curved arrows. D 2-methyloxirane Br i 2-bromopropane 4. The reaction of the epoxide with methoxide produces one of the two constitutional isomers of methoxy-methylcyclopentanol shown below. Write the steps in the mechanism for this process. Be sure to show the following: (1) the structure of any intermediates that are formed during the mechanism, (2), what, if anything, is added or lost during each step of the mechanism, (3) any non-zero formal charges found on the structures that you write. REMEMBER: You may not use any materials except those that are given in the equation. H₂C NaOMe/MeOH OH 4-methyl-2-pentanone -or- X -OH

3. Using 2-methyloxirane and 2-bromopropane as your only sources of carbon, show how you would synthesize 4-methyl-2-pentanone. Show all reagents and conditions and synthetic intermediates, but you do not need to draw any curved arrows. D 2-methyloxirane Br i 2-bromopropane 4. The reaction of the epoxide with methoxide produces one of the two constitutional isomers of methoxy-methylcyclopentanol shown below. Write the steps in the mechanism for this process. Be sure to show the following: (1) the structure of any intermediates that are formed during the mechanism, (2), what, if anything, is added or lost during each step of the mechanism, (3) any non-zero formal charges found on the structures that you write. REMEMBER: You may not use any materials except those that are given in the equation. H₂C NaOMe/MeOH OH 4-methyl-2-pentanone -or- X -OH

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

See similar textbooks

Similar questions

How would you synthesize the following compounds from cyclohexanone using reagents from the table? Use letters from the table to list reagents in the order used (first at the left). Reagents a 1. CH3MgBr / dry ether 2 H3O+ e 1. OsO4 i 1. BH3/THF 2. NaHSO3/H₂O 2. H₂O₂ / NaOH b 1. C6H5 MgBr / dry ether f 1. NaBH4 j Mg / dry ether 2 H3O+ 2. H3O+ C PBг3 g HOCH2CH2OH/HCI k H2/Pd d m-chloroperbenzoic h H3O+ / heat 1 CrO3 / H3O+ acid a) 2-phenylcyclohexanone b) cyclohexylbenzene m cyclohexanone
How would you synthesize the following compounds from cyclohexanone using reagents from the table? Use letters from the table to list reagents in the order used (first at the left). Reagents a 1. CH3MgBr/dry ether 2 H3O+ e 1. OsO4 i 1. BH3/THF 2. NaHSO3/H2O 2. H₂O₂ / NaOH b 1. C6H5MgBr / dry ether f 1. NaBH4 j Mg / dry ether 2 H3O+ 2. H3O+ с PBr3 g HOCH2CH2OH/HCI k H2/Pd d m-chloroperbenzoic h H3O+ / heat I CrO3 / H3O+ acid m cyclohexanone a) cyclohexylbenzene b) 2-phenylcyclohexanone Submit Answer Try Another Version 3 item attempts remaining
3. Perform a retrosynthetic analysis on the following alkene. Show both ways of making it from alkyl halides and carbonyl compounds. After you have shown both syntheses, suggest which of the two would be a better one. Show both starting material combinations with your model kit and share pictures. Using the model kit will help you with getting the answer.
What product(s) will you expect from A? From B? How will the ethoxide in ethanol and t-butoxide in t-butanol affect (if at all) the product of the reactions? Note that both have the same alkyl halide as starting metarial.
2. Propose multi step synthetic routes from 1-butanol and the given organic molecule to the indicated product. You must use the given organic starting materials. You can use any organic solvent, any amine, and any of the following inorganic chemicals: CO2, KCN, Mg, Li, Cul, Zn, Sn, HCl, H2O, H2SO4 DIBALH, LiAlH4, NaBH4, CrO3, H2 and Pd catalyst, PBr3 and SOCI2. e) Hint: You must use CO 2. e) Hint: You must use CO2. OH 3 Ĉ my
Choose the right reagent or series of reagents from the ones listed below to prepare 2-pentanone from acetylene. NaNH2NaNH2 followed by CH3CH2CH2BrCH3CH2CH2Br, then disiamylborane followed by H2O2H2O2, HO−HO− H2H2, Lindlar followed by H2OH2O, H+H+ NaNH2NaNH2 and CH3CH2CHOCH3CH2CHO NaNH2NaNH2 followed by H2OH2O, H+H+ NaNH2NaNH2 followed by CH3CH2CH2BrCH3CH2CH2Br, then H2OH2O, H2SO4H2SO4, HgSO4 Choose one.
A chemist needs an ether to use as a solvent for a reaction and wants to synthesize it in one step from two of the following available reagents: sodium ethoxide, bromomethane, potassium tert-butoxide, and 2-bromo-2-methylpropane. i) Which combination(s) will give a good yield of an ether? Illustrate, showing the mechanism of the reaction. ii) Illustrate with a mechanism the reaction of one of the combinations that will not yield an ether?
b. Design the syntheses of the following three compounds, i, ii, and iii using the starting materials provided along with any reagents discussed in CHEM2401 and CHEM2402. The starting materials need to be transformed for the development of the reaction pathways and cannot be used directly to form the products. These are multiple step syntheses. Starting materials: ΌΗ مجھ ہم مجھ لة
Complete the synthesis of ethyl (E)-2,2,4-trimethyl-3-oxo-5-phenylpent-4-enoate from the starting material given (ethyl propionate). You must list out all reagents/solvents next to the reaction arrows and draw the intermediate structures in the boxes. I am giving you one restriction. You are not allowed to introduce any enolates as reagents next to the reaction arrows. orff ion
Complete the synthesis of ethyl (E)-2,2,4-trimethyl-3-oxo-5-phenylpent-4-enoate from the starting material given (ethyl propionate). You must list out all reagents/solvents next to the reaction arrows and draw the intermediate structures in the boxes. I am giving you one restriction. You are not allowed to introduce any enolates as reagents next to the reaction arrows.
How would you synthesize the following substances from benzaldehyde and reagents from the table? In general, the fewer the steps, the better the synthesis. You should not need more than four steps. Use letters from the table to list reagents in the order used (first at the left) with no commas. Example: cag Reagents a CH2=0 f 1. CH3MgBr / dry ether 2 H3O+ j 1. P(C6H5)3 2. BuLi b O g Dess-Martin periodinane KA Br2 in CH2Cl2 C (C6H5)3P+-CH2 h 1. NaBH4 1. PBг3 2. H3O+ d m NH + acid i 1. BH3/THF NaNH2/NH3 2. H2O2 / NaOH e CrO3/H3O+ n Mg/ dry ether a) Previous Next
2. Propose an efficient synthetic route for each the following multi-step reactions after demonstrating retrosynthesic analysis (identifying the last step first; working backwards from product to reactant). Show the starting materials, intermediates, and products. isopentane a. 3-methylbutan-1-ol b. Но- HO с.