3. Enumerate the purposes of regular blood sugar monitoring in Type 2 Diabetes Mellitus 4. Discuss how obesity or weight gain increases the risk

Essentials of Pharmacology for Health Professions
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Author:WOODROW
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Chapter10: Poison Control
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3. Enumerate the purposes of regular blood sugar monitoring in Type 2 Diabetes Mellitus

4. Discuss how obesity or weight gain increases the risk of developing Type 2 Diabetes Mellitus.

5. Upon reviewing the record of the patient in the given case, which of the medication stated on the list causes
diabetes and weight gain? Explain the mechanism of causing the said adverse effects. 

SH: Has been married for 21 years. She has two children who are teenagers. She works in a floral shop making deliveries.
Denies any use of tobacco products but does drink alcohol occasionally (five beers/wine per week).
Meds: Glyburide 5 mg po BID, Lisinopril 20 mg po once daily, Zyprexa 5 mg po Q HS, Carbamazepine 200 mg po TID,
Lorazepam 1 mg po TID PRN, Fluoxetine 20 mg po Q AM, EC ASA 81 mg po once daily, Pravastatin 40 mg po once
daily
All: Morphine-hives
ROS: Complaints of nocturia, polyuria, and polydipsia on a daily basis. Denies nausea, constipation, diarrhea, signs or
symptoms of hypoglycemia, paresthesias, and dyspnea.
Objective
PHYSICAL EXAMINATION
Gen: WDWN severely obese, Caucasian woman in NAD
VS: BP 165/90, P 98, RR 18, T 38.6°C; waist circ 38 in, Wt 109 kg, Ht 5'8"
HEENT: PERRLA, EOMI, R, and L fundus exam without retinopathy
Neck/Lymph Nodes: WNL
Lungs: Clear to A & P
CV: RRR, no MRG
Abd: NT/ND
Genit/Rect: Deferred
MS/Ext: Carotids, femoral, popliteal, and right dorsalis pedis pulses 2+ throughout; left dorsalis pedis 1+; feet
show mild calluses on MTPs
Neuro: DTRs 2+ throughout, feet with normal sensation (5.07 monofilament) and vibration
LABORATORY EXAMINATION
Na 139 mEq/L
K 3.6 mEq/L
Cl 103 mEq/L
CO₂ 31 mEq/L
BUN 15 mg/dL
SCr 0.8 mg/dL
Gluc (random) 232 mg/dL
UA: 1+ protein, (+) microalbuminuria
Ca 9.4 mg/dL
Phos 3.3 mg/dL
AST 15 IU/L
ALT 18 IU/L
Alk Phos 62 IU/L
T. bili 0.4 mg/dL
AIC 9%
Fasting Lipid Profile:
T. chol 236 mg/dL
LDL 135 mg/dL
HDL 56 mg/dL
Trig 223 mg/dL
TC/HDL ratio 4.2
Transcribed Image Text:SH: Has been married for 21 years. She has two children who are teenagers. She works in a floral shop making deliveries. Denies any use of tobacco products but does drink alcohol occasionally (five beers/wine per week). Meds: Glyburide 5 mg po BID, Lisinopril 20 mg po once daily, Zyprexa 5 mg po Q HS, Carbamazepine 200 mg po TID, Lorazepam 1 mg po TID PRN, Fluoxetine 20 mg po Q AM, EC ASA 81 mg po once daily, Pravastatin 40 mg po once daily All: Morphine-hives ROS: Complaints of nocturia, polyuria, and polydipsia on a daily basis. Denies nausea, constipation, diarrhea, signs or symptoms of hypoglycemia, paresthesias, and dyspnea. Objective PHYSICAL EXAMINATION Gen: WDWN severely obese, Caucasian woman in NAD VS: BP 165/90, P 98, RR 18, T 38.6°C; waist circ 38 in, Wt 109 kg, Ht 5'8" HEENT: PERRLA, EOMI, R, and L fundus exam without retinopathy Neck/Lymph Nodes: WNL Lungs: Clear to A & P CV: RRR, no MRG Abd: NT/ND Genit/Rect: Deferred MS/Ext: Carotids, femoral, popliteal, and right dorsalis pedis pulses 2+ throughout; left dorsalis pedis 1+; feet show mild calluses on MTPs Neuro: DTRs 2+ throughout, feet with normal sensation (5.07 monofilament) and vibration LABORATORY EXAMINATION Na 139 mEq/L K 3.6 mEq/L Cl 103 mEq/L CO₂ 31 mEq/L BUN 15 mg/dL SCr 0.8 mg/dL Gluc (random) 232 mg/dL UA: 1+ protein, (+) microalbuminuria Ca 9.4 mg/dL Phos 3.3 mg/dL AST 15 IU/L ALT 18 IU/L Alk Phos 62 IU/L T. bili 0.4 mg/dL AIC 9% Fasting Lipid Profile: T. chol 236 mg/dL LDL 135 mg/dL HDL 56 mg/dL Trig 223 mg/dL TC/HDL ratio 4.2
Subjective
Chief Complaint: "I was recently diagnosed with possible diabetes and would like to have my blood sugar tested. I think
that my blood sugar is running low because I have a terrible headache."
HPI: Sarah Martin is a 43-year-old woman who comes to the pharmacy for a diabetes education class taught by the
pharmacist. She would like for the pharmacist to check her blood sugar before the class begins. She was diagnosed with
diabetes mellitus Type 2 about 6 months ago. She has been attempting to control her disease with diet and exercise but
has had no success. Her physician has recently started her on glyburide 5 mg. She has gained 15 lb. over the past year.
She monitors her blood sugar once a day, per her physician, with a range of 215-260 mg/dL. Her fasting blood sugars
average 170 mg/dL.
PMH: Type 2 DM x 6 months, HTN × 15 years, bipolar disorder × 25 years, Dyslipidemia × 10 years, Morbid obesity *
15 years
FH: Father has a history of HTN and bipolar disorder. The mother has a history of dyslipidemia. Brother has DM secondary
to alcoholism.
Transcribed Image Text:Subjective Chief Complaint: "I was recently diagnosed with possible diabetes and would like to have my blood sugar tested. I think that my blood sugar is running low because I have a terrible headache." HPI: Sarah Martin is a 43-year-old woman who comes to the pharmacy for a diabetes education class taught by the pharmacist. She would like for the pharmacist to check her blood sugar before the class begins. She was diagnosed with diabetes mellitus Type 2 about 6 months ago. She has been attempting to control her disease with diet and exercise but has had no success. Her physician has recently started her on glyburide 5 mg. She has gained 15 lb. over the past year. She monitors her blood sugar once a day, per her physician, with a range of 215-260 mg/dL. Her fasting blood sugars average 170 mg/dL. PMH: Type 2 DM x 6 months, HTN × 15 years, bipolar disorder × 25 years, Dyslipidemia × 10 years, Morbid obesity * 15 years FH: Father has a history of HTN and bipolar disorder. The mother has a history of dyslipidemia. Brother has DM secondary to alcoholism.
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