3) Indicate the order in which the metabolites in citric acid cycle are produced; acetyl CoA as 1 and oxaloacetate as 9. Metabolites in Citric Acid Cycle Enzyme involved in the formation of Order the metabolite Acetyl CoA 1 Oxaloacetate 9. Succinyl SCOA Fumarate Malate Citrate Succinate a-Ketoglutarate Isocitrate
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- Understanding the Mechanism of Hemolytic Anemia Genetic defects in glycolytic enzymes can have serious consequences for humans For example, defects in the gene for pyruvate kinase can result in a condition known as hemolytic anemia. Consult a reference to learn about hemolytic anemia, and discuss why such genetic defects lead to this condition.Arrange the steps of breakdown of oleic acid (pictured below) in the correct order. 1 2 3 4 5 activation by acyl-CoAsynthe ✓ [Choose ] one cycle ofß-oxidationbeginning at the enoyl-CoAhydratasestep three cycles ofẞ-oxidation five cycles ofß-oxidation activation by acyl-CoAsynthetase enoyl-CoAisomeraseactivity enoyl-CoAisomeraseactivity V one cycle ofß-oxidationbegini V five cycles ofß-oxidation OHB1. Complete the Kreb's Cycle Acetyl CoA Citric Acd Malate dehydrogenase NADH NAD Isocitrate NAD Isocitrate Fumarase dehydrogenase NADH Fumarate NAD" FAD COASH Succinate dehydrogenase Succinate Succinyl CoA Succinyl CoA synthetase B2. How many ATP molecules can be produced from 4 molecules of Acetyl CoA if all of them enter the Kreb's Cycle? Assume all the energy yielding products enters the electron transport chain.
- Please state if the statements are true or false.1. When fructose forms its Haworth projection, it usually assumes a pyranose structure2. The conversion of 1 mole aplha-ketoglutarate to 1 mole succinyl CoA produces 2 moles of carbon dioxideLook at this diagram of fally acid metabolism and malch the numbers wilh the enzymes, inlermediatos and colactors listed Not all Ghe labels are needed and some may be uzed more than once Fatty Acid 1 2 Step 1 R-CH-CH,-CH- S-COA (Acyl CoA) 3 Acyl CoA dehydrogenase (Enoyl CoA) R-CH C=C-C-S-COA Step 2 Enoyl Co A hydratase OH H (L-Hydroxyacyl CoA) R-CH C-C-C-8-COA Step 3 L-Hydroxyacyl COA dehydrogenase R-CH C-CH-C-s-COA Ketoacyl CoA Step 4 B-ketothiolase C-S-COA R-CH-C-S-CoA (Acyl CoA-2C) A NADP E NAD C. ATP D. NADPH t. ADP t. NADH FADH2 K. coonzymeA LAMtransicnaat M. FAD >>>> > > > > Back to Step 1asap
- Which enzyme is used for both the synthesis and breakdown of acetoacetate? thiolase O HMG-CoA synthase OB-hydroxybutyrate dehydrogenase O B-Ketoacyl-CoA transferaseA. Identify different types of organic reaction mechanims in the followingmetabolic pathways.1. Catabolism of triacylglycerols- beta-oxidation pathway2. Biosynthesis of fatty acids from Acetyl CoA3. Glycolysis (from glucose to two molecules of pyruvate)4. Conversion of Pyruvate to Acetyl CoA5.Citric acid cycle6. Gluconeogensis pathway (pyruvate to glucose) B. Identify at most 5 organic reactions for each metabolic pathway.1 2 points Order the following TCA cycle metabolites in the order they are produced in one turn of the citric acid cycle. Not all answers will be used. 2 1 4 3 TI Isocitrate Citrate Lactate Pyruvate Oxaloacetate Isocitrate Succinyl-CoA Aconitate 3-Phosphoglycerate -DO
- v Hydroxy methyl glutaryl coA Match the following metabolites with the correct metabolic pathway v Propionyl-CoA A. Kreb's cycle v Dihydroxy acetone phosphate B. Soluble fiber fermenta v succinyl co-A C. Cholesterol synthesis v Hydroxy methyl glutaryl coA D. glycolysis v Hydroxy-butyrate E. Beta oxidationUsing the list of enzymes given below, provide all chemical structures and reactions for complete metabolism of the fatty acids 8:0, 18:145 and 12:247,10. It is unnecessary to repeat a reaction once it has been drawn out previously. Refer to the repeated reaction by group and number. Use the next pages if necessary and clearly identify which fatty acid is being metabolized.Complete the interrelated pathways by choosing the necessary metabolite, enzyme, coenzyme, reaction, and metabolic pathway. UDP- glucose 1- phosphate glucose-6- phosphate ribulose S-phosphate glucose 4. reduced coenzyme glycogen Ala 1. pathway 2. metabolite Pyruvate Glu 3. enzyme 7. reaction NH. 5. pathway ATP + HCO. acetyl CoA +3cetcacetate oxaloacetate 6 final oxidized product fumarate auraruuo & pathway citrulline