please help with 2e? 2c. Provide genotypes for the following individuals based on the pedigree. Use a "?" if an allele cannot bedetermined from the information given. Do not assume partners are unaffected so use "?" when an allelecannot be determined.Dylan's partner:David's father:David's mother:Sofia's mother:Sofia:Diego:Isabella:Camila:2d. What is the probability that Isabella's future daughter would be affected by ichthyosis if her partner isunaffected? Explain.2e. What is the probability that Isabella's future son would be affected by ichthyosis? Explain.' 2. David has ichthyosis, which is an X-linked recessive skin condition that is caused by a deficiency of theenzyme steroid sulfatase. The deficiency disrupts cholesterol sulfate metabolism; cholesterol sulfate plays arole in maintaining skin integrity. The normal shedding of dead skin cells is inhibited, and skin cells buildup and clump into scales. The application of skin softening creams, lotions and other topical treatmentslessens the severity of symptoms.David's partner Sofia is the daughter of David's maternal aunt. David and Sofia have two sons, Diego andDaniel, and one daughter, Isabella, all of whom have ichthyosis. They also have two unaffected daughters,Mia and Camila. David's maternal grandfather, Dylan, is also affected by ichthyosis.2a. Based on the family described above, draw a pedigree indicating individual names, biological sex(square or circle), affected/unaffected (shaded/unshaded), and relationship connections. If the individual inthe pedigree has not been specifically mentioned to have ichthyosis, assume they do not have the condition.2b. Describe how the pedigree you drew is consistent with X-linked recessive inheritance? Explain youranswer by providing at least TWO pieces of evidence taken from the pedigree.

2e) The mode of inheritance is a pattern of obtaining parentral alleles or genes to the offsprings.…

Answered: 2e. What is the probability that…

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Biology

2e. What is the probability that Isabella's future son would be affected by ichthyosis? Explain.

Biology (MindTap Course List)

11th Edition

ISBN:9781337392938

Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg

Publisher:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg

Chapter16: Human Genetics And The Human Genome

Section16.3: Genetic Diseases Caused By Single-gene Mutations

Problem 7LO: State whether each of the following genetic defects is inherited as an autosomal recessive,...

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