27. The drug cytochalasin B3 blisks the polymentation of actin muroims Which of the following events of the cell cycle in animal cells would be mod dertly dispued by cytochalasim B? A spindle famation B. spindle attachment to kinetochores C movement of chromosomes to the poles during anaphase. D cleavage furrow formation and kinesis 28. Which of the following pairs of molerades make up an MP A a growth factor and misotic facti B. ATP synthetase and a protease C. cyclin and tubulin D. cyclin and a cyclin-dependent kinase 29. Which of the following statements best describes what would happen if MPF (maationing factor) is introduced imo intature fiog oocytes that are arrested in Ci A. The cells would remain arrested in 0₂ B. The cells would enter Go

Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter28: Dna Metabolism: Replication, Recombination, And Repair
Section: Chapter Questions
Problem 19P: Figure 28.11 depicts the eukaryotic cell cycle. Many cell types “exit� the cell cycle and...
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27. The drug cytochalasin B3 blisks the polymentation of actin muroims Which of the following events of the cell cycle in animal cells would be mod dertly dispued by cytochalasim B? 

A spindle famation

B. spindle attachment to kinetochores C movement of chromosomes to the poles during anaphase. 

D cleavage furrow formation and kinesis

28. Which of the following pairs of molerades make up an MP A a growth factor and misotic facti

B. ATP synthetase and a protease

C. cyclin and tubulin D. cyclin and a cyclin-dependent kinase

29. Which of the following statements best describes what would happen if MPF (maationing factor) is introduced imo intature fiog oocytes that are arrested in Ci A. The cells would remain arrested in 0₂

B. The cells would enter Go

C. The cells would enter milis

D. The cells would begin DNA synthesis

30, If all chromosomes are not attached to the mitotic spinitie at the M pluse checkpot, the cells would most likely be arrested at which of the following points in the cell division cycle or minnis?

A. telophase B. prophase

C. G₂ D. metaphase

31. Which of the following molecules is synthesized at specific times during the cell cycle and forms an active complex with a kinase?

A. PDGF

B. MPF C cyclin

D. Cdk

32. Which of the following statements best describes density-dependent inhibition? A. As cells become more numerous, they begin to squeeze against each other, restricting their size. B. As cells become more numerous, the cell surface proteins of one cell contact the adjoining cells,

and they signal each other to stop dividing C. As cells become more numerous, the protein kinases they produce begin to compete with each other, such that the proteins produced by one cell essentially cancel those produced by its

neighbor. D. As cells become more numerous, the level of waste products increases, which slows metabolism and inhibits growth.

33. Which of the following characteristics would be most important for a chemotherapeutic drug

designed to treat cancer cells?

A. It is safe enough to prevent all apoptosis. B. It does not interfere with metabolically active

C. It specifically inhibits cells entering Go

cells.

D. It specifically inhibits the cell division cycle in rapidly dividing cells

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