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2.5-L bench scale bioreactor is used for the production of recombinant P64K protein from Neisseria meningitides. The dimensions for the bioreactor are Dt 12.9 cm, ratio Di/Dt = 1/3 and N = 700 rpm. With the scale up factor of 2.24, determine the impeller tip speed (m/s) for the pilot scale bioreactor based on constant impeller tip speed and constant power consumption per volume. Predict which scale up method might give a higher concentration of P64K, if the demand of dissolved oxygen plays an important role.

2.5-L bench scale bioreactor is used for the production of recombinant P64K protein from Neisseria meningitides. The dimensions for the bioreactor are Dt 12.9 cm, ratio Di/Dt = 1/3 and N = 700 rpm. With the scale up factor of 2.24, determine the impeller tip speed (m/s) for the pilot scale bioreactor based on constant impeller tip speed and constant power consumption per volume. Predict which scale up method might give a higher concentration of P64K, if the demand of dissolved oxygen plays an important role.

Elements Of Electromagnetics
Elements Of Electromagnetics
7th Edition
ISBN:9780190698614
Author:Sadiku, Matthew N. O.
Publisher:Sadiku, Matthew N. O.
ChapterMA: Math Assessment
Section: Chapter Questions
Problem 1.1MA
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2.5-L bench scale bioreactor is used for the production of recombinant P64K protein from Neisseria meningitides. The dimensions for the bioreactor are Dt 12.9 cm, ratio Di/Dt = 1/3 and N = 700 rpm. With the scale up factor of 2.24, determine the impeller tip speed (m/s) for the pilot scale bioreactor based on constant impeller tip speed and constant power consumption per volume.

Predict which scale up method might give a higher concentration of P64K, if the demand of dissolved oxygen plays an important role.

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