2. A newly synthesized protein contains a signal peptide on the N-terminus end of its polypeptide chain. Which of the following is not possible? A. This protein is a membrane receptor B. This protein is the protein kinase A C. This protein is insulin D. This protein is a sodium/potassium pump E. This protein is an ion channel

2. A newly synthesized protein contains a signal peptide on the N-terminus end of its polypeptide chain. Which of the following is not possible? A. This protein is a membrane receptor B. This protein is the protein kinase A C. This protein is insulin D. This protein is a sodium/potassium pump E. This protein is an ion channel

Biology (MindTap Course List)

11th Edition

ISBN:9781337392938

Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg

Publisher:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg

Chapter4: Organization Of The Cell

Section: Chapter Questions

Problem 8TYU: All of the following are true of integrins except (a) they are receptor proteins (b) they help...

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All of the following are true of integrins except (a) they are receptor proteins (b) they help organize the cytoskeleton (c) they are part of the ECM (d) they are important in cell signaling (e) they are located in the plasma membrane
A signal peptide is found at the N-terminus of a newly generated protein's polypeptide chain. Which is not possible? Options: This protein is a sodium/potassium pump This protein is a membrane receptor This protein is the protein kinase A This protein is insulin This protein is an ion channel
14) Which of the following correctly ranks the steps in the secretory pathway? 1. Active PKA subunits phosphorylate targets in the cell, regulating function. 2. The catalytic subunits of PKA dissociate. 3. Gprotein a subunit exchanges bound GDP for GTP. 4. CAMP binds to the regulatory subunits of PKA, activating it. 5. Ga subunit dissociates from complex and activates adenylate cyclase. 6. Ligand (hormone) binds to receptor. 7. Activated adenylate cyclase produces CAMP from ATP.
1. A protein has seven transmembrane domains, one loop to bind a ligand, one loop to bind a G protein. This protein is: A. A RTK receptor B. A voltage dependent ion channel C. A ribosome D. A GPCR receptor E. A second messenger
Imagine that there is a mutation in the SRP receptor that disrupts its function. What is the logical outcome of this? Select all statements below that are true. Oa. SRP will no longer bind to the signal peptide O b. Membrane protein insertion will no longer occur correctly O c. SRP will no longer bind the SRP receptor O d. Vesicular movement from the ER to Golgi is inhibited O e. Proteins are no longer able to enter the secretory system
Which of the following steps occurs first in cell to cell communication? O A membrane protein changes conformation OA ligand binds to a receptor O A G-protein is activated O A docking protein is phosphorylated Previous
7. Describe a ligand-gated channel signal pathway. What effects can opening or closing an ion channel have on cells? What type of cell is generally associated with this pathway?
Table 1. The most common endogenous opioid peptides produced in humans Рeptide Enkephalins Leu-enkephalin YGGFL Met-enkephalin YGGFM Metorphamide YGGFMRRV-NH2 Peptide E Peptide Sequence YGGFMRRVGRPEWWMDYQKRYGGFL Endorphins B-endorphin Y-endorphin a-endorphin YGGFMTSEKSQTPLVTLF KNAIIKNAYKKGE YGGFMTSEKSQTPLVTL YGGFMTSEKSQTPLVT Dynorphins Dynorphin A Dynorphin B Dynorphin1-8 YGGFLRRQ a-neoendorphin YGGFLRKYPK B-neoendorphin YGGFLRKYP YGGFLRRIRPKLKWDNQ YGGFLRRQFKWT
1. Based on the following description, draw the cell signaling pathway described (you only need to draw the pathway in one cell, but show the type of signaling described – you may need 2 diagrams). Compound X is released from cells in the pancreas and activates cells in the liver. What general type of cell signaling is this? When compound X binds its receptor on a liver cell, some of the amino acids (Y – one letter amino acid code) on the cytoplasmic side of the receptor are phosphorylated. Label what type of receptor this is. This leads to the receptor activating a cytoplasmic protein F which then activates a kinase K which then activates protein Z (diagram what is happening here – how is protein Z activated). Protein Z activation results in several genes being expressed. Label all your parts (don’t forget to label the ligand). Circle the signal transduction pathway and put a box around the cell response.
1. EGF interacts with blank to activate the MAP kinase cascade? G protein coupled receptor; receptor Tyrosine kinase; serine/threonine kinase; cdk 2. When a trimetric G protein is activated by gpcf? The three subuni8of the G protein remain tightly associated with each other; the GDP bound to the a subunit is phosphorylated to form bound GTP; it dissociates into a free b subunit as an ay subunit; none
. which of the following statements about heterotrimetric G proteins and their receptors is incorrect? A: when GTP binds to the alpha subunit of the G protein, the beta-gamma subunit dissociates from the alpha subunit B: G-protein coupled receptors contain nine transmembrane alpha helices C: binding of arrestin causes removal of the receptor from the membrane D: G protein- coupled receptors may be desensitized by serine phosphorylation I had chosen option A and got it wrong. What is the Correct answer and explain how it is. Also, where did i go wrong in choosing option A?