1°What components of the plasma membrane might you drug interact with? Explain can use as many components as you need (may need more or less).
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- What components of the plasma membrane might this drug interact with? Explain can use as many components as you need (may need more or less). Component 1 and why: Component 2 and why: Component 3 and why:An amino acid mixture consisting of phenylalanine, glycine, and glutamic acid is to be separated by HPLC. The stationary phase is aqueous and the mobile phase is a solvent less polar than water. Which of these amino acids will move the fastest? Which one will move the slowest?Diffusion experiments of a small molecule drug in tissue samples are performed. The drug has a radius of 2.24 nm and a pure-water diffusivity of 2.75 x 10^-6 cm^2/s. Cells occupy approximately 72% of the tissue byvolume. The molecule is very hydrophilic and does not readily cross cellular membranes. If you assume that the interstitial space is gel-like with a microstructure parameter k=3.7 x 10^-3 nm^-1, what is the effective diffusivity in the tissue?
- You are working on a team that is designing a new drug. For this drug to work, it must enter the cytoplasm of specific target cells. Which of the following would be a factor that determines whether the molecule selectively enters the target cells? O the phospholipid composition of the target cells' plasma membrane O the nonpolar, hydrophobic nature of the drug molecule the similarity of the drug molecule to other molecules that are transported into the target cells the concentration of the drug molecule that is transported in the blood Submit Request Answern. What is the average distance traversed by a membrane lipid in 1 μs, 1 ms, and 1 s?34: Which of the following best describes how high levels of cholesterol affect the cell membrane at certain temperatures? At high temperatures, high amounts of cholesterol decrease the rigidity of the cell membrane. At low temperatures, high amounts of cholesterol increase the rigidity of the cell membrane. At low temperatures, high amounts of cholesterol increase the fluidity of the cell membrane. At high temperatures, high amounts of cholesterol increase the fluidity of the cell membrane.
- ;, Consider a spherical cell at body temperature (37°C) that is 10 µm in radius. The concentration of ions inside and outside the cell are given below. Sodium and potassium are the only permeant ions, and the membrane contains proteins that pump in 3 sodium ions for every 2 potassium ions pumped out. [Na*] = ? [K*] = 119mM [Ci] = 8mM [A] = 121mM [Na*] = 120mM [K*] = ? [Cr] = 125MM [glu] = ? (a) Suppose the cell is in osmotic equilibrium, find the 3 unknown concentrations. (b) Suppose the membrane conductance to sodium is 5% that to potassium, find the resting membrane potential via circuit analysis. (c) What would the resting potential be if the membrane were instead permeable only to chloride ions? (d) Suppose the cell was suddenly placed in distilled water, what would happen to it? And, how much external pressure (positive or negative) would be needed to prevent this from happening?Matching: (one answer can be matched to more than one questions). An answer can be used more than once to match a question. Figure 1 1 Figure 2 ✓ The structure shown in Figure 1 is a ✓ The structure shown in Figure 2 is a ✓Drug 1 (triangle) that is encapsulated in between the bilayer structure needs to be a drug. ✓ Drug 2 (diamond) that is encapsulated in the core needs to be a ✓ Drug 3 (pentagon) that is encapsulated in the core needs to be a drug drug. A. hydrophobic B. hydrophilic C. Liposome D. MicelleOsmosis Practice Activity Osmosis is the diffusion of water from an area of high concentration to an area of low concentration. Only water moves in osmosis! The diagrams below show the concentration of water and salt inside the cell and the concentration of water and salt surrounding the cell. Complete the sentences below by comparing the concentration of the water inside the cell and the concentration outside the cell. 1. a. Water will flow the cell, out of the cell, in both directions). (into 5% NaCl 95% H20 95% NaCI 5% H20 b. The cell will (shrink, burst, stay the same). a. Water will flow (into the cell. 2. 5% NaCl out of the cell, in both directions). 5% NaCl 95% H20 95% H20 b. The cell will (shrink, burst, stay the same).
- a cell defense worksheet (1) [Compatibility Mode] Qv Search in Document Insert Draw Design Layout References Mailings Review View Acrobat + Sha 三,三, Century Gothic , 12 A A- Aa A IU abe X, x² Styles Styles Pane Create and Share Reque Adobe PDF Signatu What does polar mean? Hydrophilic Step 8: Insert channel proteins into the membrane. Transport substances across the membrane. Note: You can only transport substances using channel proteins until there were What is this process called? Step 9: Moving from to concentration requires the use of energy to substances. This is called transport and uses: (place answer in table) 1. 2. Which is cell Step 10: Carbohydrates are like identification badges. Cells that have different membrane The immune system uses the carbohydrates to carbohydrates do different that your cells belong to and are not or other foreign cells. What does the immune system do to foreign invaders? 149% E Focus 目 Page 2 of 3 505 words English (United States) MAR 15 MacBook Air…The distribution of water is determined by solute concentrations. A hypertonic solution would cause a body cell to shrink in size. Both statements are true. Both statements are false. The first statement is true and the second statement is false. The first statement is false and the second statement is true. Spaced practice question: Consider a membrane protein and its chemistry. Which of the following would describe a channel protein? It is an inorganic compound. It is an example of a globular (functional) protein. It is stable when exposed to an acidic environment. It is an example of a fibrous (structural) protein.Explain tonicity. Define the terms hypertonic, hypotonic, and isotonic and explain how they relate to the movement of water and solutes in solution. Be sure to use the words swelling, lysis, and crenation (shriveling) in the discussion.