10. The normal pH of the stomach is around 3. A patient takes an antacid which raises the buffered pH of their stomach to 5. Assuming a stomach volume of 5.0 x 102 mL of fluid (also assume that the fluid in the stomach is a simple aqueous buffer), what percentage of a 4.0 x 102 mg dose of naproxen will be dissolved given the following information: Naproxen is a neutral weak acid with a pKa of 4.2 Intrinsic solubility (So) of naproxen = 0.07 mg/mLwollot erl lo airlw nt a. <25% b. Between 25% and 50% C. Between 51% and 75% 2 Hq d d. >75%

Principles of Modern Chemistry
8th Edition
ISBN:9781305079113
Author:David W. Oxtoby, H. Pat Gillis, Laurie J. Butler
Publisher:David W. Oxtoby, H. Pat Gillis, Laurie J. Butler
Chapter15: Acid–base Equilibria
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10. The normal pH of the stomach is around 3. A patient takes an antacid which raises the
buffered pH of their stomach to 5. Assuming a stomach volume of 5.0 x 102 mL of fluid
(also assume that the fluid in the stomach is a simple aqueous buffer), what percentage
of a 4.0 x 102 mg dose of naproxen will be dissolved given the following information:
Naproxen is a neutral weak acid with a pKa of 4.2
Intrinsic solubility (So) of naproxen = 0.07 mg/mLwollot erl lo airlw nt
a. <25%
b. Between 25% and 50%
C. Between 51% and 75%
2 Hq d
d. >75%
Transcribed Image Text:10. The normal pH of the stomach is around 3. A patient takes an antacid which raises the buffered pH of their stomach to 5. Assuming a stomach volume of 5.0 x 102 mL of fluid (also assume that the fluid in the stomach is a simple aqueous buffer), what percentage of a 4.0 x 102 mg dose of naproxen will be dissolved given the following information: Naproxen is a neutral weak acid with a pKa of 4.2 Intrinsic solubility (So) of naproxen = 0.07 mg/mLwollot erl lo airlw nt a. <25% b. Between 25% and 50% C. Between 51% and 75% 2 Hq d d. >75%
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