Write the correct letter 1.The -glycosidic bond in uridine phosphate exist betweena) C1 of ribose and N9 of uracilb) C3 of ribose and N9 of uracilc) C1 of ribose and N1 of uracild) C3 of ribose and N5 of uracil2.Which of the following DOES NOT describe the promoter region?a) occurs in the region preceding the message sequence that defines the RNAb) found upstream of the transcription start sitec) found on the DNAd) they are transcribed to RNA sequences3.lf the sequence of a segment of an RNA transcript is given as: 5'-UCGCCAAUCGGU-3', whatis the sequence in the DNA coding strand?a) 3'-AGCGGTTAGCCA-5'b) 3'TCGCCAATCGGT-5'c) 5-TCGCCAATCGGT-3'd) 5'-AGCGGTTAGCCA-3'4. A double-stranded DNA is 15 percent cytosine. How many percent is thymine?a) 15%b) 25%c) 35%d) 85%

1. The glycosidic linkage involves c-1 of sugar and the hydrogen atom of N-1 in uracil 2 Promoters…

Answered: 1.The -glycosidic bond in uridine…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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the chemical group responsible for nucleophilic attack in translational elongation is a) free alpha-NH2 group on amino acid of A site aminocyal tRNA b) the 3=hydroxyl on the 3' end ribose c) the oxygen on the alpha phosphate of the incoming NTP d) the 5= hydroxyl on the 5' end deoxyribose e) an oxyanion on the Y-phosphate of the dNTP
1. True or False a) DNA bases, when coiled to histones, become inaccessible to RNA polymerase. b) Methylation silences the gene expression. c) Poly-A tail is added to the growing mRNA prior to translation.
If the following nucleotide sequence represents the active domain of the COVID19’s M-protein 5’ ---- 5’ GGGUACAUGGUAGCCCCCGUCGAGAAAACACCC …. 3’ a) describe a potential mutation that may occur and the mechanism that could fix it b) if the repair mechanism is faulty, explain the consequences for COVID19 & that of the infected individual
Given the following DNA sequence from the template strand of a given gene: 5'CTTGCGTCACCTAAGACCTGTCATCG3' a) Write the mRNA that will be transcribed from the DNA sequence above (be sure to label the 5' and 3' ends) b) Write the peptide sequence translated from the mRNA produced in part a.
The ribosome is the target for many important antibiotics. Distinct antibiotics inhibit various steps in the translation process. Please specify which step of the translation (one short sentence is sufficient) each antibiotic below targets (ex: kasugamycin – inhibits formation of the initiation complex) a) chloramphenicol b) tetracycline c) erythromycin d) aminoglycosides such as kanamycin
29. Huntington disease results from expansion of a CAG triplet within the first exon of the huntingtin (HD) gene. This genetic defect most likely results in which of the following? DA) Abnormal polyglutamine tract within the huntingtin protein B) Abnormal splicing of huntingtin mRNA C) Decreased transcription of huntingtin mRNA D) Premature translation termination E) Shifted translation frame ined
There may be more than one answer for each Expression of mRNA can be regulated by which of the following? a.) RNA interference b.) presence of vectors c.) antisense RNA d.) blocking of poly(A)polymerase Which of the following occur during processing of pre-mRNA? a.) removal of exons b.) removal of noncoding sequences c.) addition of 5’ cap structure d.) addition of poly-A tail
Write the terms that match the definitions given below. A) A sequence in the leader region of the mRNA thought to be responsible for routing the mRNA on the small ribosomal subunit at the beginning of translation. B) In prokaryotes, a promoter consensus sequence located 10 bases upstream from the first base transcribed. C) In eukaryotes, a promoter consensus sequence located 70 bases upstream of the first base to be transcribed. D) In eukaryotes, a promoter consensus sequence located 25 bases upstream from the first base transcribed.
Which of the following statements concerning the sequence of events involved in the initiation of transcription by E. coli RNA polymerase are correct? ( can bemore than one) A.)Initiation starts with a pyrimidine nucleotide triphosphate. B.)The sigma factor (σ) functions during initiation of transcription. C.)Initiation starts with a purine nucleotide triphosphate, which is destined to become the 5'-end of RNA. D.)Initiation starts with a purine nucleotide triphosphate, which is destined to become the 3'-end of RNA. E.)RNA polymerase binds to the DNA at a point approximately 35 bp upstream of the start of transcription, at a sequence TTGACA. F.)The sigma factor does not dissociate until RNA elongation is complete.
5. a) Describe, using a diagram or point form notes, what is happening during transcription and translation of protein synthesis. Indicate where these events take place in the cell. b) An error occurs in the transcription of the original master strand of DNA. At the very first base pair, a guanine is substituted for cytosine. State the possible effects on the polypeptide and its functions.
1. true or false a) Capping is the process of adding poly-guanido methyl in the mRNA. (true/false) b) In a nucleosome (histone-DNA structure), the histone is highly positively charged. (true/false) c) The presence of lactose in E.coli triggers the transcription of Lactose Operon.
1.) Define transcription and translation. How does transcription and translation differ in prokaryotes vs. eukaryotes (i.e. What is present in one but not the other)? 2.) What it means when we say that genetic code is redundant? 3.) Describe the stages of transcription (in detail for each step) - what components are required? 4.) Describe the stages of translation in eukaryotes (initiation, elongation, termination)

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