1.(a) () Trace the course of [1,6-(C-14)-2,5-(C-13)]glucose that is first processed through glycolysisand proceeds into the TCA cycle. For the glycolysis part, use the diagram below to decide where glucoseatoms end up in pyruvate. You need to illustrate only the structures of D-glucose, labeling the atoms, andof pyruvate, labeling the origin of the atoms in glucose and the distribution of the carbon isotopes in py-ruvate. After one round of the TCA cycle where will the labeled carbons be found?HOHO(b) (*CH₂OHGlucoseHO+ 2 NAD+O + 2 NADH+ 2 Pi2F0+ 2 ATPOH + 2 ADP3 + 2 H₂OPyruvateThe formation of oxaloacetate in the TCA cycle is unfavorable with a AG'° = +29.7kJ/mol. Write the reactions using structural formulas for the formation of oxaloacetate and for thesubsequent reaction in the TCA cycle. What particular part of the subsequent reaction makes it veryfavorable and ensures that oxaloacetate is continually removed to make the next TCA intermediate?

Approach to solving the question: (a) To trace the course of [1,6-(C-14)-2,5-(C-13)]glucose through…

Answered: 1.(a) ( ) Trace the course of…

Biochemistry

6th Edition

ISBN:9781305577206

Author:Reginald H. Garrett, Charles M. Grisham

Publisher:Reginald H. Garrett, Charles M. Grisham

Chapter18: Glycolysis

Section: Chapter Questions

Problem 6P: The Reactions and Meehanisms of the Leloir Pathway Write the reactions that permit galactose to be...

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