1. Four genes (A,B,C,D) of a bacterium code for four enzymes (A,B,C,D), which act sequentially to catalyze the production of compound D, as follows. enzyme A enzyme B enzyme C enzyme D precursor -----> compound A -----> compound B -----> compound C -----> compound D A number of mutant strains of the bacterium are isolated, which grow only on supplemented media, as outlined below. Medium supplemented with Compound A Compound B Compound C Compound D Strain 1 No growth No growth Growth Growth Strain 2 No growth Growth Growth Growth Strain 3 No growth No growth No growth Growth a. The mutation in strain 1 is in which gene? How do you know? ✓✓ b. The mutation in strain 2 is in which gene? How do you know? ✓✓ c. The mutation in strain 3 is in which gene? How do you know? ✓✓
1. Four genes (A,B,C,D) of a bacterium code for four enzymes (A,B,C,D), which act sequentially to catalyze the production of compound D, as follows. enzyme A enzyme B enzyme C enzyme D precursor -----> compound A -----> compound B -----> compound C -----> compound D A number of mutant strains of the bacterium are isolated, which grow only on supplemented media, as outlined below. Medium supplemented with Compound A Compound B Compound C Compound D Strain 1 No growth No growth Growth Growth Strain 2 No growth Growth Growth Growth Strain 3 No growth No growth No growth Growth a. The mutation in strain 1 is in which gene? How do you know? ✓✓ b. The mutation in strain 2 is in which gene? How do you know? ✓✓ c. The mutation in strain 3 is in which gene? How do you know? ✓✓
Chapter10: Reconstitution Of Powdered Drugs
Section: Chapter Questions
Problem 5.2P
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Transcribed Image Text:1. Four genes (A,B,C,D) of a bacterium code for four enzymes (A,B,C,D), which act sequentially to
catalyze the production of compound D, as follows.
enzyme A
enzyme B
enzyme C
enzyme D
precursor -----> compound A -----> compound B -----> compound C -----> compound D
A number of mutant strains of the bacterium are isolated, which grow only on supplemented media, as
outlined below.
Medium supplemented with
Compound A
Compound B
Compound C
Compound D
Strain 1
No growth
No growth
Growth
Growth
Strain 2
No growth
Growth
Growth
Growth
Strain 3
No growth
No growth
No growth
Growth
a.
The mutation in strain 1 is in which gene? How do you know? ✓✓
b. The mutation in strain 2 is in which gene? How do you know? ✓✓
c. The mutation in strain 3 is in which gene? How do you know? ✓✓
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