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- Arrange the compounds below in order of increasing reactivity in a SN2 reaction. 1. (CH3)2СНCI 2. CH3CH2B1 3. CH3CH2C1 A) 1; 2; 3 В) 3;B 2; 1 C) 1; 3; 2 D) 2; 1; 3 E) 3; 1; 2For the given molecule, highlight any nucleophilic sites in red and any electrophilic sites in blue. O: 439 0-HIdentify which is nucleophile / electrophile. Identify if it is neutral or charged nucleophile or electrophile :0: 6. :0 :0: H3C H3C C-H H. 7. :0: :0: H. Н—с—Br: CH3 e.. :Br: H3C° H3C н H. :0-I I I
- Which nucleophile would prefer simple addition over conjugate addition? CH3MgBr NaCN CH3CH2NH2 (CH3CH2)2CuLiOrganic Chemistry - nucleophilic substitution and elimination rxns chapterRank the following in increasing order of reactivity towards nucleophilic acyl substitutiona. CH3COCl, CH3COOCH3, CH3CONH2b. CH3COOCH3, CH3COOCH2CCl3, CH3COOCH(CF)3
- 2) Rank these molecules by their SN2 reaction rate. If a difference in reaction rate is hard to predict, you may group molecules with similar reactivity. CI CI Br CI CI A D E BExplain why quinuclidine is a much more reactive nucleophile thantriethylamine, even though both compounds have N atoms surroundedby three R groups.10. Which molecule would be most likely to react via SN1 mechanism? A. B. C. D. CI CI CI fe CI
- Match the species with the description of its reactivity. alkene chloride 1. nucleophile carbocation 2. electrophile HCIAcyl transfer (nucleophilic substitution at carbonyl) reactions proceed in two stages via a "tetrahedral intermediate." Draw the tetrahedral intermediate as it is first formed in the following reaction. H3C HCI / H2O `NH2 reflux • You do not have to consider stereochemistry. • Include all valence lone pairs in your answer. • Do not include counter-ions, e.g., Na", I, in your answer. • In cases where there is more than one answer, just draw one. opy aste Previous NextOrder the following compounds from least reactive to most reactive with MeMgBr.