0 d. 11 О е. 19 это Ø Consider the pedigree illustrated above (i.e., Figure E in the supplemental file). How many individuals shown in the pedigree are deceased? 0 а.2 0 b.6 О с. 8 QUESTION 35 Ø
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- 1 p The pedigree below shows the blood types of the Jones family. Review the pedigree and determine the possible genotype(s) of individual 12. AB AB #11 #12 #13 O a. AA O b. 1A Oc. i O d. Only a and b are possible genotypes O e. All of these are possible genotypesII III IV V Study the pedigree above. 1. What type of inheritance pattern is depicted?. 2. If the discase is called M, write the genotypes of cach individual in the pedigree. Ifthe genotype cannot be determined with centainty, write the possible alternatives. 1:1 Il:1 l:1. IV:1 V:1, 1:2 I1:2 IV:2 V:2 Il:3 III:3 IV:3 V:3_ I1:4 IlI:4, IV:4 V:4, Il:5 IlI:5 IV:5 V:5 Il1:6 II:7 Ill:6, IV:6 IlII:7 IV:7 IlI:8 IV:8 12 %3DIn this case a family history revealed a genetic basis for the disorder. The pedigree is shown in Fig. 1 Below. Key Ø Female: affected Female: unaffected I || IV V TOLO 5 DO 머 9 10 a. Any of these options is possible b. III.5 but not V.3 would display the disease O c. V.3 but not III.5 would display the disease O d. Neither III.5 nor V.3 would display the disease Oe. Both III.3 and V.3 would display the disease 10 ન Male: affected Male: unaffected Deceased Disease status not given Dizygotic twins Monozygotic twins Fig. 1 Disease pedigree. Five generations I, II, III, IV, V are shown. Females are represented by circles, males by squares, dizygotic (non-identical) twins by diagonal lines originating from the same point, Monozygotic (identical) twins by diagonal lines originating from the same point and joined symbols and deceased by a diagonal line through the symbol. Filled symbols indicate that the individual displays the disease phenotype. Unfilled symbols indicate that the individual…
- A small town in north Texas is in the middle of quite a scandal. It turns out that 15 years ago, three babies were born within three minutes, and each was sent home randomly with the wrong family. In order to determine which children are actually related to the parents involved, the blood type of each individual was determined Parents Children A and AB X A YO Z AB AB and O II. O and B 5. Who are the parents of child Z? A I В. 1 С. I none of these O cUse the following pedigree to answer the questions below. Mike Henry Violet Ø Iris Saul Paul Fiona Lilly Lucas V FUE Lucy P. Tandickey an TORSHOW GIE Bob Sey Bun O Ava Casey Dan Legend Female Male 음 Male w/ Trait Female w/ trait A. Who are Fiona's parents? B. How many children did Henry and Iris have? C. Name all of the deceased people on this pedigree. D. Who did Bob have children with? E. Does Dan have the trait of interest? Deceased Female Deceased MaleFill out the blanks of the pedigree (AA, Aa, or aa) How many children did the original couple have? How many grandchildren do they have?.
- II 2 III 1 Refer to the pedigree above. What is the genotype of person II-1 if this pedigree is for hemophilia? (A dot in the centre of a symbol indicates a known carrier of a recessive trait). hh O xtxh Hh O xhy OxHy2 8. 5 6. 10 IV 3 4. 5 8. 10 11 12 13 14 Which of the following best describes the trait in the pedigree? OX-linked dominant OX-linked recessive O autosomal domiant O autosomal recessive 2)The pedigrees are for a rare autosomal trait. What is the chance that individual A is a carrier? O O 1/2 1 1/4 2/3 0 56 A ठट B
- 14) When examining a pedigree chart, I notice that only males are affected. What does this tell me about the inheritance pattern? ____________________________ __________________________________________________________________Use the pedigree to answer the questions that follow. Make sure you put your answer in the correct blank. (A) AB B ? 2 II A A AB B A AB A 1 2 6. 7. 8. II A A B 6. a) State the possible blood type(s) of individual |-4 (Blank 1) b) State the possible blood type(s) of individual I-6 (Blank 2) c) State the possible genotype(s) of individual II-5 (Blank 3) d) State the possible genotype(s) of individual II-6 (Blank 4) e) Determine the percentage chance that couple Il-4 and IIl-5 have another child that has type O blood (Blank 5) Blank # 1 Blank # 2 Blank # 3 Blank # 4 Blank # 5e last two joints of the idde inger are shortened. In the other ingers, the last two joints are fused into one and are also 4119122 --- ETee C. Brachydactyly Our Pedigree C. Brachvcactyy 2 3 4 5 8. 10 3 5 8 OL 11 12 13 14 TV 2 4 5 7 8 9 10 FIGURE 4 Formulating Generalizations 1. In pedigree A, why do parents 13 and 14 in generation III have four deaf children? 2. In pedigree A, how can parents 1 and 2 have a deaf child even though neither parent is deaf? 3. In pedigree A, why don't parents 8 and 9 and 1l and 12 have at least one deaf child? 4. List by number the persons in pedigree A for which you cannot determine a genotype. For example-II-1. 5. Why can't you determine the genotypes of these pèople? 6. In pedigree B, how can unaffected parents have an affected child? 7. What is the genotype of the mothers of all affected females in pedigree B? Explain. 8. What characteristic do all affected females in pedigree B have in common? 9. List by number the persons in pedigree B for which you…