. Due to chemotherapy, your patient is experiencing nausea and vomiting. Which of the following neuromediators is causing the nausea and vomiting? Serotonin Dopamine Acetylcholine Adrenaline Noradrenaline
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1 . Due to chemotherapy, your patient is experiencing nausea and vomiting. Which of the following neuromediators is causing the nausea and vomiting?
- Serotonin
- Dopamine
- Acetylcholine
- Adrenaline
- Noradrenaline
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- We talked about drug effects on neurons in sequence. The effect of alcohol is multi-faceted and the following question asks you to apply your knowledge. Imagine two neurons in sequence. The presynaptic neuron is GABAnergic and the postsynaptic neuron is dopaminergic. The effects of alcohol are not fully understood but it does seem to inhibit GABAnergic neurons. How would the release of dopamine from the postsynaptic neuron change in this case? Explain your answer, being sure to make each connection between concepts clear. If alcohol instead inhibited dopaminernergic neurons, in what way might the ion flow change in the dendrites of the postsynaptic neuron of this example?A medication causes sedation and diarrhea. This drug is most likely a: 1. GABA-ergic agonist and dopamine antagonist 2. opioid agonist and dopamine agonist 3. GABA-ergic agonist and adrenergic antagonist 4. opioid agonist and adrenergic agonistYou are preparing to give your patient a Beta 1 Agonist. When will you know that this medication is CONTRAINDICATED? Allergy to Aspirin Altered Mental Status High Heart Rate Low Heart Rate
- 1. Jesse age 27 complaints of muscle spasm, sweating abdominal pain and diarrhea. You know that her temperature is 101, pulse is 120 and her BP is 186/92. In reviewing her medications you note but she is taking fluoxetine (Prozac) and Sertraline (Zoloft), which life threatening events may she be experiencing? a. Neuroleptic malignant syndrome b. Monamine oxidase crisis c. Serotonin syndrome d. HyperpyrexiaDrugs that have been developed to potentiate inhibitory neurotransmitters (like gamma amino butyric acid and glycine) include all of the following except: tranquilizers tacrine ethanol valium barbituratesThe following diagram represents a typical serotonergic synapse. Where, specifically, do antidepressants work (e.g. SSRI)? Neurotransmitter Neurotransmitter transporter Аxon Synaptic vesicle terminal Voltage- gated Ca?+ channel Synaptic cleft Receptor Postsynaptic density Dendrite Neurotransmitter Synaptic Vesicle Neurotransmitter transporter (aka Reuptake transporter) Receptor O All of the above
- 1. Choose (place an X) whether the characteristic applies to the Nervous System or Endocrine System (or both) Characteristic Action is generally brief (lasting milliseconds). Action generally lasts longer (seconds to days). Mediator molecules delivered to target by bloodstream. Action potentials trigger release of mediator molecules at synapse with target. Target cells require specific protein receptor for mediator molecule. Stimulates skeletal muscle contractions. Influence is much broader; will regulate virtually all types of body cells. Controls growth & development and regulates reproductive systems. Maintains internal environments (homeostasis) Nervous Endocrine Mediator molecules include acetylcholine, glutamate, norepinephrine, serotonin Mediator molecules include aldosterone, melatonin, insulin, calcitoninA nurse is discussing how beta-blockers work to decrease blood pressure with a nursing student. Which statement by the student indicates a need for further teaching? ‘Beta-blockers block the actions of alpha receptor sites” Beta-blockers decrease heart rate and contractility Beta-blockers decrease peripheral vascular resistance Beta-blockers decrease the release of reninA patient has a tumour of the chromaffin cells in the adrenal medulla. Whilst awaiting surgery, he is treated with an antagonist which reduces the consequences of adrenal medulla overactivity by binding alpha adrenergic receptors irreversibly. Which one of the following drugs has he been treated with? Answers A - E A Clopidogrel B Lansoprazole C Aspirin Propranolol E Phenoxybenzamine
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