Quantitative Analysis Of Mefenamic Acid And Redox Titration

We know that that the end point of the titration is reached when, after drop after careful drop of NaOH, the solution in the flask retains its pale pink color while swirling for about 30

1. To titrate a hydrochloric acid solution of “unknown” concentration with standardized 0.5M sodium hydroxide.

In experiment two, the drug Panacetin was separated by a series of chemical reactions into its three components: sucrose, aspirin, and an unknown active ingredient, either acetanilide or phenacetin. The purpose of this lab was to determine what percentages of each component is present in the pain-killer. The initial step was to dissolve Panacetin in dichloromethane. However, sucrose is insoluble in dichloromethane because organic molecules are soluble in organic solvents, and dichloromethane is an inorganic solvent, so only aspirin and the unknown dissolved. By using gravity filtration, sucrose was filtered from the solution and 0.30g of solid was collected.

Titration is the slow addition of one solution of a known concentration (called a titrant) to a known volume of another solution of unknown concentration until the reaction reaches neutralisation, which is often indicated by a colour change. The solution called the titrant must satisfy the necessary requirements to be a primary or secondary standard. In a broad sense, titration is a technique to determine the concentration of an unknown solution. We can use the reaction to find out the molarity of the solution by measuring the product(s) that is formed.

Colorimetric assay is a process determining the concentration of a chemical element or compound in a solution

By first measuring the pH levels of solution A through E with a pH meter, it gives a numeric reading to ph balance to a solution. Next, add in a natural indicator called anthocyanin made from the pigment from a red cabbage into each solution and mixed it until there is a distinct color and recorded on the chart. Finally, by looking at the result of the pH reading level that

In this experiment redox-based titrimetric analysis was used to determine the amount of ascorbic acid (Vitamin C) contained in a serving of lemonade. This was done to confirm the 100 percent recommended daily allowance claimed on the package for a serving of Country Time Lemonade. The titration method used was adding a thyodene indicator to the analyte (lemonade solution) there is a visible colour change when the endpoint of the reaction between the titrant (KIO3) and the analyte occurs. The following reactions show how this titration method is viable. (Draw in reactions) KIO3 first reduced with iodide (I-) to generate iodine (I2 ) which then oxidized the ascorbic acid within the lemonade. Once all the ascorbic acid had reacted any iodine

In the titration, I used these available instruments to ensure my results would be as accurate as possible.

ii. The second part of the titration series involves titration of NaOH with Hydrochloric acid (HCL). Again, three reps of titration and a blank titration have to be completed. A volumetric pipet is used to measure 10.00mL of HCL into three labeled conical flasks. Then the flasks are filled with deionized water until about the 50mL mark. A buret is

The first titration (with use of the PASCO program) is the most accurate titration that the lab group can perform. The titration curve gives many different variables, with accuracy that passes what humans can do without a machine. But the problem with this titration is that the curve or change to neutrality can often be sudden and out of nowhere. This means that it is very hard to just titrate a solution to become neutral, and often will change into the opposite property, essentially an acid to base and vice versa. The titration with use of an indicator is less accurate, but shows a more visual representation about how a titration takes place. The change in color is a less accurate indication of the volume it takes a solution to change to be neutral, but the visual change is helpful in a classroom laboratory setting. The preference is the first titration method, because it is more accurate and can give more reliable data, since the PASCO machine and drips added are not affected by human

During a titration the pH of the solution will be monitored using a pH meter from that we get a titration curve. The titration curve is then used to determine the equivalent molecular weight and Ka value of the unknown weak acid, from that we are

At least three more titrations should be performed, this time more accurately, taking into account roughly where the end point will occur. The initial and final readings on the burette (prior to starting the titration and at the end point, respectively) should be recorded. Subtracting the initial volume from the final volume will yield the amount of titrant used to reach the

By using acid-base titration, we determined the suitability of phenolphthalein and methyl red as acid base indicators. We found that the equivalence point of the titration of hydrochloric acid with sodium hydroxide was not within the ph range of phenolphthalein's color range. The titration of acetic acid with sodium hydroxide resulted in an equivalence point out of the range of methyl red. And the titration of ammonia with hydrochloric acid had an equivalence point that was also out of the range of phenolphthalein.. The methyl red indicator and the phenolphthalein indicator were unsuitable because their pH ranges for their color changes did not cover the equivalence points of the trials in which they were used. However, the

to recognize the end point in titrations during EDTA. For instance, the concentration of a

An acid-base titration is the determination of the concentration of an acid or base by exactly neutralizing the acid/base with an acid or base of known concentration. This allows for quantitative analysis of the concentration of an unknown acid