Bios 101, Problem Set 2
These questions are due at the beginning of discussion. The due date is indicated on the syllabus. Please type or print neatly on separate sheets of paper. It is imperative that no portion of your answers be copied directly from another student or from an online source.
1. A man with normal vision marries a woman with normal vision. Their first child, a boy, is color-blind.
i) (one point) Diagram the cross above.
colorblindness: (XxXx= females; XxY=males)
mom:X dad: Y
Xx
XxX
XxY
Since its sex-linked, then you know the father has normal vision, then he has a dominant allele on his X chromosome. Since the color blind child in question is a son, then he inherited a Y from the father. So, the colorblindness
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What type of allelic interactions are these? How many loci are involved? Are there multiple possibilities? Diagram a cross consistent with the data.
ii) List and discuss several traits, in domestic plants of your choosing, that have a similar genetic basis.
3. A line of Drosophila melanogaster with ebony body and sepia eyes (line A) is crossed to a line with tan body and red eyes (line B). The F1 are all tan-bodied, red-eyed.
i) (one point) What proportion of gametes produced by the F1 have the dominant allele for both loci? What proportion of the gametes produced by line B have the d ominant allele for both loci?
Next, imagine that An F1 female is crossed to a male from line A.
If 1000 offspring were scored for both characters, what number of offspring would be expected to have each of the four phenotypes (assuming no linkage)? List them below.
Now imagine that the following data were actually collected from the cross above:
Body Eyes
Tan normal 271
Tan sepia 229
Ebony normal 220
Ebony sepia 280
ii) (one point) Are the loci linked? If so, how many map units are they apart ? Do a χ2 test and show your work below. Diagram this cross.
4. (two points) Go online, and look up two hereditary illnesses that are caused by having two copies of an autosomal recessive allele.
p2 + 2pq + q2 = 1 ; where ‘p2’ represents the homozygous dominant genotype, ‘2pq’ represents the heterozygous genotype, and ‘q2’ represents the homozygous recessive genotype
GENETIC CROSSES An “X” is used to indicate that two individuals have been mated together. The parents are designated as P (for parental) and the offspring as F (for filial). When several generations are involved, subscripts are added to designate the generations. P1 give rise to F1 (first filial) progeny. If the F1 are crossed together they become P2 and their progeny F2. A cross between members of the F1 and members of the P1 is a backcross. A cross between members of the F1 and the true breeding recessive P1 is a test cross. MONOHYBRID CROSS The simplest form of a cross is a monohybrid cross, which analyses a single trait and its associated variations. The diagram below shows the
2. Can the student tell from the blood type if the student is heterozygous or homozygous? Explain. (5 points) Yes, knowing your blood type would
What observations can you make regarding the gene pool and gene frequency of the surviving individuals?
9. No, because each child's 2 sets of chromosomes are rearranged independently, so that there is an equal probability of all of them having the same genotype (1/2^4, or 1/16) as there is of them having all different ones
4. Clear wing, Black eye, and Hairless (c, b, and h) are linked, recessive traits carried on
Suppose the feather color of a bird is controlled by two alleles, D and d. The D allele results in dark feathers, while the d allele results in lighter feathers.
2. How will the alleles for these traits assort into the gametes that each parent might produce? (Hint: For a reminder on how alleles sort independently into gametes, refer to the illustration in Part 2, Question 2, in the Student Guide.)
Now you have determined some facts about the grounded allele and the trait that it causes. Given what you know, do you expect the mutant F1 flies to be homozygous or heterozygous for the allele that causes the grounded trait? According to your reasoning, if you mated two mutant F1 flies, what percentage of flies would you expect to be wild type versus mutant in the F2 progeny? Draw a Punnett square of this cross to justify your answer.
Gathering Data on the Different Traits of the Garden Pea (Pisum Sativum), Organizing the Dominant/Recessive Phenotypes of 60 F2 Offspring and Determining Whether the Null Hypothesis is Rejected or Accepted Using the Chi-Square Test.
You are also provided with a heterozygous female, and a homozygous recessive male for a genetic cross. In this particular female, all the dominant alleles are on one chromosome, and the recessive counterparts are on the other homologous chromosome. Due to a chromosomal condition, in the female no recombination occurs between the M and N loci. Normal recombination occurs between the L and M loci. Diagram this cross, and show the genotypes and frequencies of all offspring expected from this cross.
Using the Hardy-Weinberg equation, calculate the predicted genotype frequencies for each population scenario below. Place your calculations and data in the space provided below. Once you have calculated the frequencies, answer the conclusion questions for each one. Please remember that all calculations must be shown for full credit.