The New Dictionary of Cultural Literacy, Third Edition. 2002.
syphilis
(SIF-uh-lis) A sexually transmitted disease caused by a microorganism. In its initial stages (called primary syphilis), it is manifested by a skin ulcer called a chancre. If the disease is not treated by penicillin or other antibiotics, the infection becomes chronic. In so-called tertiary syphilis, virtually any tissue in the body can be damaged, including the cardiovascular and nervous systems. The disease, if left untreated, can cause blindness, mental illness, and death.
