The amino acid histidine has ionizable groups with pKą values of 1.8, 6.0, and 9.2, as shown.H₂N-CHTCOOHpHCH₂ Hlonizable -COOHgroup=CHCOO-H₂N-CH1.8pk₁CH2-COO-H-NCH-HisH+COO-+H₂N-CH6.0pk₂CH2-HisCH-NHCOO-H₂N-CH9.2pk3CH2-N-NH₂A biochemist makes up 80 mL of a 0.11 M solution of histidine at a pH of 5.1. She then adds 60 mL of 0.10 M HCl. What isthe pH of the resulting solution?CH

The objective of this question is to find the pH of histidine.

The amino acid histidine has ionizable groups with pKa values of 1.8, 6.0, and 9.2, as shown. COO™ COO™ H₂N-CH H₂N-CH CH H CH N bbbb 6.0 CH H N COOH H₂N-CH CH₂ H -N CH lonizable -COOH group 1.8 COO -HisH+ -His CH -NH COO™ H₂N-CH 9.2 CH, H H N -NH₂ CH A biochemist makes up 80 mL of a 0.11 M solution of histidine at a pH of 5.1. She then adds 60 mL of 0.10 M HCl. What is the pH of the resulting solution?

The amino acid histidine has ionizable groups with pKa values of 1.8, 6.0, and 9.2, as shown. COO™ COO™ H₂N-CH H₂N-CH CH H CH N bbbb 6.0 CH H N COOH H₂N-CH CH₂ H -N CH lonizable -COOH group 1.8 COO -HisH+ -His CH -NH COO™ H₂N-CH 9.2 CH, H H N -NH₂ CH A biochemist makes up 80 mL of a 0.11 M solution of histidine at a pH of 5.1. She then adds 60 mL of 0.10 M HCl. What is the pH of the resulting solution?

General, Organic, and Biological Chemistry

7th Edition

ISBN:9781285853918

Author:H. Stephen Stoker

Publisher:H. Stephen Stoker

Chapter20: Proteins

Section: Chapter Questions

Problem 20.48EP: Most amino acids have isoelectric points between 5.0 and 6.0, but the isoelectric point of lysine is...

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The amino acid histidine has ionizable groups with pKa values of 1.8, 6.0, and 9.2, as shown. COOH H₂N-CH CH₂ H 2 -N H lonizable group 6.0 1.9 7.94 0.11 N H CH -COOH H₂N-CH | CH₂ H 2 N 1.8 COO- I pk₁ C H COO- CH -HisH+ H₂N-CH 6.0 COO- pk ₂. CH₂ H 2 H -His N CH COO™ H₂N-CH 9.2 pk 3 CH₂ H -N с H —NH — —NH, A biochemist makes up 95 mL of a 0.11 M solution of histidine at a pH of 5.1. She then adds 60 mL of 0.10 M HCI. What is the pH of the resulting solution? N CH
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