ow can these physiological factors listed below affect drug effect? Explain each. - diurnal rhythm - acid - base balance - hydration - electrolyte balance
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.) How can these physiological factors listed below affect drug effect? Explain each.
- diurnal rhythm
- acid - base balance
- hydration
- electrolyte balance।
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- For a lipid-soluble drug that has very poor aqueous solubility, what strategies could be used to make this drug more bioavailable after oral administration? This under Bipharmaceurics and Pharmacokinetics subjectCan you determine why some drugs have narrower spectra thanothers? (Hint: Look at their mode of action.)1.) How can these physiological factors listed below affect drug effect? Explain each. - diurnal rhythm - acid - base balance - hydration - electrolyte balance 2.)1.) How can these pathological factors listed below affect drug effect? Explain each. - Gi disorders - Vascular disorders - Liver dysfunction - Kidney dysfuntion
- 1.) How can these physiological factors listed below affect drug effects? Explain each. - diurnal rhythm - acid-base balance - hydration - electrolyte balance 2.)1.) How can these pathological factors listed below affect drug effects? Explain each. - Gi disorders - Vascular disorders - Liver dysfunction - Kidney dysfunctionIn drug study about folic acid what will be the mechanism of action,contraindication,and side effects?Please help me out ... The drug dosage for the patient is calculated using a BSA of 1.9m2. If the order is 15mg per m2, how many milligrams is the desired dose?
- a drug that will be administered as a 500mg oral solution has the following average pharmacokinetics parameters Ka= 1hr, Cl= 10l/he, V= 100ml, F= 0.5 what concentration would you expect 4 hr after the doseCHM3413-Neutral vs lonized... consider the table of drugs shown below and their respective pka value(s). Complete the table by drawing the relevant portion of the drug molecule in its IONIZED form. Indicate whether the ion is the conjugate acid or conjugate base of the neutral drug, if two pka values are listed, then two ionized structures must be drawn. Drug Name: Neutral Form (Neutral) pka from table HA BH+ 5.4 9.5 Baclofen Captopril Ampicillin 3.7 M 9.8 2.5 7.2 Doxycycline 3.4 9.5 7.7 H H₂C HS 1,0 NH₂ Pho OH OH NH H OH S CH₂ NCH₂ OH 0 150 ONN-C H OH 0 CON 6 M lonized Form(s) Is/are the ION(s) a conj. acid or conj, base? CA or CB? % ionized at physiological pH?Can you determine why some drugs have narrower spectra than others?
- List three types of chemical reactions that prepare drug molecules for excretion from the body.rug-B has an elimination half-life of 9 hours, an absorption half-life of 20 minutes and linear harmacokinetics. In a patient, the plasma concentration five hours from the administration of two 60 mg cablets of the drug is 8 ug/mL. What would you expect to be the plasma concentration five hours from the administration of one 60 mg tablets? 1 ug/mL Answer 1-1compare the efficacy and potency of each of the following: Furosemide Hydrochlorothiazide Morphine Heroino Demerol compare the efficacy and potency. Include references in APA format to support your response.