Describe how the activity and specificity of ribonucleotide reductase (RNR) is regulated.
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Describe how the activity and specificity of ribonucleotide reductase (RNR) is regulated.
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- What is the role of ATP(CTP): tRNA nucleotidyletransferase?After being stabilized with supplemental oxygen, a blood transfusion, and medication to help with the pain, JJ was prescribed the drug hydroxyurea to help increase the level of fetal hemoglobin (ay2) in the red blood cell. Though the exact pharmacological effect of hydroxyurea is unclear in the treatment of Sickle Cell Disease, it is known that the drug is an inhibitor of ribonucleotide reductase and acts to transiently inhibit deoxyribonucleotide synthesis in dividing cells. Q5: In which phase of the cell cycle does hydroxyurea produce its main effect?Describe the path for the synthesis of TTP from UTP.
- Illustrate the pathways to synthesize the following amino acids: glutamine, serine, arginine, glycine, and cysteine.What is the properties of ribonuclease enzyme and describe what reaction it catalyzes?Describe the reactions catalyzed by nucleoside phosphorylase, adenosinedeaminase, and xanthine oxidase.
- Explain why RNase A cannot catalyze the hydrolysis of DNA.In Metabolic Pathways, what are the nucleotide-containing compounds?In the: Inhibition of splicing by ribozymes Explain: (a) What is the process affected? (b) What is the Effect on the process? (c) Does it affect prokaryotes, eukaryotes or both?