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- (a) What is the dosage form of the two above drugs? (b) What is the administration method for the two above drugs? Molnupiravir has not been approved but has been authorized for emergency use by the FDA under an EUA to treat mild to moderate COVID-19 infection. Briefly explain this decision made by FDA based on the knowledge of clinical trials. Both drugs are not allowed to be prescribed to person under 18 years old due to insufficient clinical data. Why is it necessary to separately conduct clinical trials for a younger age group?1) COVID-19 a. Should there be clinical trails performed by agents (institutions) outside the very drug companies that manufacture them? b. Which factors influence the form of treatment in any given nation (example, amount of moeny, profits to be made, accessibility of the treatment, etc.) c. Which type od approaches you think may work the best in form of minimizing COVID-19 infections and the resulting side effectsIn caring for a patient receiving therapy -ith a myelosuppressive antineoplastic drug, the nurse notes an order to begin filgrastim after the chemotherapy is completed. Which statement correctly describes -hen the nurse -ill begin the filgrastim therapy? a) It can be started during the chemotherapy.b) It -ill begin immediately after the chemotherapy is completed.c) It -ill be initiated 24 hours after the chemotherapy is completed.d) It -ill not be started until at least 72 hours after the chemotherapy is completed.
- (c) Molnupiravir has not been approved but has been authorized for emergency use by the FDA under an EUA to treat mild to moderate COVID-19 infection. Briefly explain this decision made by FDA based on the knowledge of clinical trials. (d) Both drugs are not allowed to be prescribed to person under 18 years old due to insufficient clinical data. Why is it necessary to separately conduct clinical trials for a younger age group?Which antiretroviral drug class does Zidovudine (AZT) belong to? a) Non-nucleoside reverse transcriptase inhibitors (NNRTIs) b) Nucleoside reverse transcriptase inhibitors (NRTIs) c) Protease inhibitors d) Integrase inhibitorsa recent communicable disease outbreak, except COVID-19. For the selected communicable disease outbreak, the following MUST be clearly identified: a) a description of yellow fever b) who was affected c) location of the outbreak d) the When (time) e) Why the outbreak occurred (fully described what was the cause). f) Provide relevant data and appropriate references.
- Which of the following statement is false regarding the SARS-CoV-2 protease Mpro? a) Mpro catalyze the translation of viral RNA into polyproteins b) Mpro is an ideal drug target because its structure is largely conserved across the SARS-CoV family c) N3 is an irreversible inhibitor that block the substrate binding site of Mpro d) Mpro forms a dimeric structure and each protomer is composed of three domainsBelow, you can see a picture of an antimicrobial drug. Regarding semi-synthetic antimicrobial drug development to try to avoid development of antibiotic resistance, use 1 sentence to address what is the significance/value of the presence of the various R-groups (e.g. R4, R5, R6, etc.)?"out Document1 - Word References Mailings 1. Search Review View Help Answer the questions A) What is the most common anesthetic to use in animals for induction under anesthesia? B) What are the side effects of using Propofol in animals? C) How and with what will the animal be "scrubbed" after it is under anesthesia and ready for the doctor? D) What is the purpose of SPO2 and where is it put in the animal? E) What is the purpose of the ECG and where are they placed on the animal?
- Below is the structure of an intercalating agent. By making reference to the structure of the compound, outline the essential structural features for the activity of intercalating drugs acting on DNA.1. a)how is it possible for such drugs to selectively kill bacterial cells and not our own cells? b)Provide an example of post-translational regulation of protein activity and explain the advantage of regulating each protein/process at the post-translational level instead of the transcriptional level.Explain the drug discovery process of Losartan? Please explain at your own words.