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- HBY-BIO-U2-TEST BIOCHEMISTRY-SY 20-21 Which statement BEST explains why enzymes bind to specific substrates? O Anenryme can be inibted se ds active site is altered An enzyme faids ditterently in the presence of diferent substrates O Diferert amino acd seguences cause variations in the shapes of an enzymes active sites O Enzymesubstrate binding is based on sze so ony large enrymes can bind to large ubstratesSPS Date: Page No. A pulse af 13-14c] of pyruate con tans 4c) js methylgiaup. added toa do0lated mitachondria. Prruiate (the 'Riuspension of solated mitochondoria Aften (Q ane tuen of c gcid cycle, which canlion co e (ore) labeled in Daaloocetate? he citri'c loore) labeledin Draw f caid crle infermedictes t shau hene the labreled the structures ALL the cetrec tohone canban ie ih erch one. (t How needed to nelecse caribon many tong the Gycle would te Eycle,Wou all the labeled as 1"cog? Explain your answer.23 Which statement describes a disease state caused by altered protein structure? A silent mutation in hyaluronidase disnupts mucosal function OA slent mutation in arachidonic acid disrupts eicosanoid production O A missense mutation in heokinase disrupts glycolysis OA ronsense mation in ATP disrupts energy metabolsm
- AM Fri May 21 Take Quiz Coenzymes function to O denature the enzyme, stopping the chemical reaction from occurring. interact directly with enzymes, either enabling the reaction to occur or making the substrate-enzyme interaction more efficient. O change the shape of enzymes, allowing different additional substrates to bind. O dilate blood vessels, allowing more blood to flow, allowing more substrate to reach enzymes. O absorb excess hydrogen and hydroxide ions, keeping the pH relatively stable, so that reactions can occur most efficiently. Question 11 1 In the digestive system, which major organ starts the breakdown of proteins? O Mouth O Large intestines O Small intestines O Stomach O Esophagus Question 12 energy is energy found in the bonds of ingested nutrients.>MK585652.1 Sardinella tawilis voucher TaSt3 cytochrome oxidase subunit 1 (COI) gene, partial cds; mitochondrial GGTGCTTGAGCAGGGATAGTAGGGACTGCCCTAAGTCTCCTAATTCGGGCGGAGCTAAGCCAGCCCG TTTCTTCATAGTGATGCCAATTCTAATTGGGGGTTTTGGGAACTGGCTCGTCCCTCTAATGATCGGGGC TTCTCCTAGCCTCTTCGGGCGTAGAGGC GGGCAGGGACGGGTTGAACAGTATACCCGCCCTTGGO ATCTCGTCAATTCTTGGGGCGAT ACCACAATTATTAATATGAAACCCCCTGCAATT CAGTCCTGGCTGCCGGGATCACTATGCTATTAACAGATCGAAACTTAAATACAACTTTCTTCGACCCTGCAGGAGGAGGAGACCCAATTCTATACCAACACCT The highlighted text refers to the Gene origin Gene identity Accession number O Species identity GGACGACCAGATTTACAACGTCATCGTCACGGCACATGCCTTCGTAATGAT TCCCGCGAATAAACAACATGAGCTTCTGGCTCCTTCCCCCTTCCTTCCTTC of the sequence? SGGGCCTCTGTCGACCTTACCATCTTCTCACTCCACCTAGCAGGT TTGAGCTGTTCTCGTAACCGCTGTGCTTCTCCTTCTCTCCCTTCBSC1010C Enzymes & Cellular Regulation Dr. Harris 4. Compare the rate of the pepsin-catalyzed reaction at pH = 1.5 with the rate of the lipase- catalyzed reaction at pH = 1.5. 5. Compare the rate of the pepsin-catalyzed reaction at pH = 8.0 with the rate of the lipase- catalyzed reaction at pH = 8.0. 6. Based on your understanding of protein structure, explain in detail the effect of exposing an enzyme to a pH outside its optimal range. Include a discussion of the effect on both the structure and function of the enzyme. 7. At what pH values is lipase likely to be denatured? Explain your answer.
- O Login - Sr Cycle - 4447214 A @ Tools Add-ons Help Last edit was 2 hours ago al text Arial 12 BIUA 2 wwww p gr I| 3 I 4 5 | 6 13. This new compound with one fewer phosphate groups is called adenosine diphosphate (ADP). What does the prefix "di" mean? 14. Compare the structural formulas of ADP and ATP and complete the table below, ATP ADP Number of ribose molecules Number of adenine molecules Number of phosphate molecules Which one is formed when ATP loses a phosphate group? Mark only one box. WHich one is formed when ADP gains a phosphate group? Mark only one box. Part IlI: Changing ADP to ATP DELLxplain the most important ceason whiy enzymer are necescary in anchemical feactions.12 Avdil DiC diLei OcL 27 dl 1.Jopm nents Enzyme Reaction Rates ts prary racker 10 20 30 40 50 2 4 6. 8. 10 Temperature (°C) pH Based on these data, this enzyme functions best at what temperature and pH? Remind O Temperature of 27°C and a pH of 4 O Temperature of 40°C and a pH of 8 Four O Temperature of 50°C and a pH of 10 Calculator O Temperature of 37°C and a pH of 6
- enzyme active site Ser-CH₂-C 195 Asp 102 substrate 15. A substrate binds to enzyme active site. a) List the roles of serine, histidine and aspartic acid b) Show how the first tetrahedral intermediate would be formed. c) Show acyl-enzyme intermediate. d) What is the pka for Histidine? How is this pka relate to physiological pH (7.4)? Do you anticipate any enzymatic reaction will occur if histidine is replaced with cysteine? Why?urses / MEDBAS145en 21-22Spring / 2021-2022 Spring Semester / Final Which of the following pairs depict the absolute specificity of the enzyme? Select one: O O O O a. All of them b. Hexokinase - Glucose c. Lactase - Lactose d. Lipase - Triacylglycerol3:43 ll LTE O moellim.riphah.edu.pk Biochemistry-l Dashboard / My courses / Biochemistry-II | General / QUIZ 1 Question 7 Not yet answered Marked out of 1.00 P Flag question ADP will the regulatory enzymes of TCA cycle? Select one: O a. None O b. Both depending on condition O c. Inhibit O d. Activate Next page Course Outline
