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- 5. Which Sharpless Asymmetric Dihydroxylation reagent and substrate would you use to make this diol? OH orloo он ? ?Synthesize the following compound from cyclohexanol using any other organic or inorganic compounds. HO. Part 1 out of 2 Preparation of the Grignard reagent: Book rint rences OH draw structure ... draw structure... Draw the intermediate product formed above and select the correct reagent A. O MgBr, O CH;Br O Brz PB13 Draw the intermediate product formed above and select the correct reagent B. O MgBr O Mgo O O Mgl, O Mg Hint Prev 3 of .8 Next > re to search1. Williamson Ether Synthesis Questions for lab , Synthesize phenacetin from acetaminophen (Tylenol) via a Williamson ether synthesis. a.Find the missing reagent:CH3CH2OH +? → C2H5OC2H5 H2SO4, H2O HNO3, H2CO3 b.What is the nucleophile in this reaction? H2O Nu- RO- ROH c.If you wanted to prepare Guaifenesin (present in OTC cough meds), choose the alcohol you would start with? 2 methoxy benzoinc acid 2-methoxy benzaldehyde 2-methoxyphenol 2 methoxy anisole d.What was the mechanism of the reaction you used to prepare the ether? SN1 SN2 E1 E2 e.The reaction given below is known as by which o the following reaction? C2H5ONa+IC2H5→C2H5OC2H5+NaI Oxidation reaction Williamson reduction reaction Williamson ether synthesis Wittig synthesis f.Chloroethane reacts with X to form diethyl ether. What is X?…
- 7. Devise a synthesis of each compound from the given starting material. You may use any needed organic or inorganic reagents. More than one step may be required. Me OH ...Br ??? Eto Me ☑OH Me OH Z ??? ...Br Me OH ....OMeWhich of the following molecules is most nucleophilic? OA. NaOCH₂CH3 OB. CH3CH₂OH OC. NaOC6H5 OD. C₂H5OH 1 E.CH3COONa1. Provide the mechanism of the reaction shown in the picture. 2. Explain why it cannot be done in basic conditions. 3. Why is the enol tautomer favored over the keto tautomer? Ph H3C OH H H3O+/H₂O HO H3C Ph
- Which reaction (s) does an anhydride produce? HO. NEl3 CI КОН I. calor OK II NH2 O. IV HO HO. calor III a. Ob., IV Oc. I, II d., II, III, IV1.What is the best reagent to complete this synthesis? OA 1)???? CN 7.) NaCN.7. Circle the best substrate for a nucleophilic substitution reaction. OH OCH3 SH CI
- IWhat is the intermediate A for the following Stork enamine synthesis? O. CI 1. H,C. CH3 C12H1402 p-TSOH (-H,O) 2. H3O* A.Devise a 4-step synthesis of the product from the starting material. CH3 1. reagent 1 2. reagent 2 H3C HO. 3. reagent 3 4. reagent 4 H3C H. Select reagent 1: Select reagent 2: NH, CH,, cat. H,0+ CH, MGB. Select reagent 4: H, Pd NaBH, LIAIH,3. Show the mechanism for the following addition/substitution. cat. H2SO4 MeNH2 remove H₂O H H Why doesn't a primary amine need to add a second nucleophile? (i.e. why does it make an imine instead of an aminal?)
