3. Draw both hemiacetal forms of d-ribofuranose and both hemiacetal forms of d-xylofuranose.
Q: 14.0 12.0 10.0 8.0 pH 6.0 4.0 2.0 0.0 0.5 1.0 1.5 2.0 2.5 14.0 12.0 10.0 8.0 6.0 4.0 2.0 3.0
A: Isoelectric point is the pH at which the amino acid carries no net charge. It is given by the…
Q: Which of the following statements is/are TRUE for the urea cycle? It has a direct link with the TCA…
A: Urea cycle is central pathway for the production of urea. Urea production is important as NH4+…
Q: Which of the following enzymes below is/are involved in the control of Krebs' cycle? citrate…
A: Kreb cycle also known as TCA cycle. It occur in matrix of mitochondria in eukaryotes and cytosol in…
Q: Calculate the amount of ATP that can be produced from one molecule of 8:0 fatty acid metabolized…
A: 8:0 fatty acid means its a 8 carbon saturated fatty acid with no carbon-carbon double bond. A 8:0…
Q: The organic compounds deposited on the electrodes in the Miller-Urey experimental setup? A…
A: Abiogenesis is the generation of life from non-living matter. Our current understanding of chemical…
Q: RNA plays a major role in the synthesis of which organic compound? Once energy is liberated from…
A: RNA is a type of nucleic acid with structural similarity to DNA but RNA is single stranded. RNA is…
Q: Sometimes scientists have too much time on their hands! In a 2013 study it was reported that Proline…
A: The total proline in our final 1 ml solution comes from 2 different sources. First source is 10 mg…
Q: 1. Draw the structures of the 20 biologically active AA. Under each structure, write the name,…
A: Amino acids are compound containing C, H, O and N. They act as building blocks ( monomer) of…
Q: Which of the following statements is are TRUE? Ca pathway involves a single C02 fixation step. In…
A: CAM pathway is cruassulacean Acid metabolism which is an adaptation by plants that survive arid…
Q: 1.-Ultrastructural organization of the eukaryotic cell structure and functional significance of its…
A: Two types of organisms are prokaryotic and eukaryotic. Prokaryotic organisms are singled cell…
Q: What is the product of the glyoxylate cycle used by growing seedling? I. glucose II. NADPH III. C02…
A: Glyoxylate cycle is an anabolic pathway which occurs in specialised organelles called glyoxysomes.…
Q: 1. Human dietary intake of carbohydrates should be less than 50% carbohydrates by mass. True or…
A: All the 4 tue and false are answered in next step. 1. Human dietary intake of carbohydrates should…
Q: Levels of structure in a protein (primary, secondary, tertiary, quaternary): What each of these…
A: Protein is a biomolecule consisting of amino acids joined together via peptide bond. Each amino acid…
Q: Which of the following is a true representation of the experimental design and results? Choose one:…
A: Low pH means a higher concentration of H+ ions. The experiment was conducted to determine whether…
Q: Which of the following 1-C unit:carrier pairing is/are correct? a.biotin:C02 b.THF:-CH2-…
A: Biotin is a co-factor that carries CO2 and regulates the activities of enzymes like acetyl-CoA…
Q: I have the substrate concentration as 20, 40 , 65 and the V(mol/min) no inhibitor 602, 690, 833 and…
A: MM plot is Michaelis menton plot that is constructed with Substrate concentration on x axis and Vo…
Q: Active transport requires energy released by an exergonic process such as the formation of ATP…
A: Active transport system requires energy in order to allow the movement of molecules, mostly the…
Q: Write TRUE or FALSE. If false, write the word/s that make(s) the statement incorrect. A glycosidic…
A: Similar to Deoxyribose Nucleic Acid(DNA), RNA(Ribose Nucleic Acid) is a linear polymer composed of…
Q: Which of the following is the correct sequence in the ETC? A. NADH → CoQ → cytochrome c → Fe-S →…
A: Oxygen is essential for living organisms for their survival. Lack of oxygen leads to the death of…
Q: 1. A simplified structure of the peptide Lys-Glu-Ser with just the ionizable groups in the charged…
A: The given peptide contains two amino groups and two carboxylic groups as ionizable groups. The pKa…
Q: A cell in a hypertonic solution swells because of a net loss of water by osmosis. True False
A: A hypertonic solution is a solution that contains high solute concentration. Osmosis is the…
Q: 2. Draw a dipeptide with a trans linkage and a net charge of -1 at pH 7 a. Indicate which six atoms…
A: The peptides are composed of twenty standard amino acids that differ from each other in their…
Q: Which of the following is/are (a) ketopentose? A. threose B. xylulose C. arabinose D. mannose
A:
Q: he Calvin cycle can be divided into which two stages? a.Preparation, fixation, reshuffling,…
A: Calvin cycle or C3 cycle can be divided into three main stages: 1. Carbon fixation 2. Reduction 3.…
Q: Determine the original polypeptide sequence that would give the following results. Amino acids…
A: Peptides are polymers of amino acids linked via a covalent peptide bond. The peptide bond formation…
Q: Proteins tracked by fluorescence recovery after photobleaching (FRAP) showed that they are ALL…
A: Introduction: Fluorescent markers get excited at a particular wavelength of light and undergo…
Q: Outline the principle behind the following techniques:…
A: Immunofixation is an immunological technique that involves antigens and antibodies. Southern blot is…
Q: Which of the following is/are (a) product(s) of the digestion of starch after the release of the…
A: Starch is composed of amylose and amylopectin. Amylose is a polymer of glucose sugars bonded via…
Q: In fatty acid biosynthesis, where does the addition of unsaturation to the hydrocarbon tall occurs?…
A: Fatty acid (FA) biosynthesis occurs in the cytosol of the cell by the Fatty acid synthase enzyme…
Q: Vasopressin: CYFQNCPRG Oxytocin: CYIQNCPLG Calculate the pI of each peptide. How…
A: Vasopressin is a antidiuretic hormone and regulates the water homeostasis, its major function are -…
Q: Which of the following is/are TRUE about the ETC? A Complex IV: last e- acceptor is Cu2+ B…
A: The electron transport chain ( ETC) is a process in which the NADH and FADH2 produced during…
Q: The above reaction coordinate diagram in the presence of enzyme is inconsistent with the "lock and…
A: Enzymes are protein molecules that increase the rate of reaction by decreasing the activation…
Q: 50 words essay on how important to have adequate knowledge of biochemistry in understanding…
A: The study of biological processes at the cellular and molecular levels using chemistry is known as…
Q: Following the production of membrane extracts using the non-ionic detergent Triton X-100, you…
A: The methods for cell disruption are host-dependent, and the techniques for recovering membrane…
Q: Which of the following cellular activity or function requires the presence of carbohydrates on…
A: Carbohydrates are biomolecules that are used as the primary source of energy by the body. They can…
Q: ELISA link____ to___ in order to create a colorimetric assay
A: Antigens and antibodies react specifically to form the Antigen-Antibody complex. Based on this…
Q: Part B. Carbohydrate, lipid, prote Based on the rules you developed in Part A, identify the…
A: The biological macromolecules can be classified into proteins, nucleic acids, lipids and…
Q: Detail the function of amino group, carboxyl group and R group found in Tyrosine
A: Tyrosine is a non-essential amino acid that is coded by UAC and UAU. It is a protein target for…
Q: The movement of water through a semipermeable membrane from a region of lower solute concentration…
A: A semi-permeable membrane is a membrane which allows partial transfer of molecules through it i.e.,…
Q: Which of the following pair of substances are products of the citric acid cycle? a) Acetyl CoA and…
A: Introduction: The citric acid cycle also known as Kreb's cycle is the final common oxidative…
Q: essay on how important to have adequate knowledge of biochemistry in understanding pharmacology
A: Biochemistry is the Study of life processes or biological processes by applying the knowledge of…
Q: Which of the following is/are true about the Cellular Membrane Structure: A. All membranes from…
A: The cell membrane, also known as the plasma membrane or cytoplasmic membrane, is a biological…
Q: Why did chemistry talk about the genetic disease?
A: Introduction Genetic disorder - A disease or disorder that is inherited genetically. Some examples…
Q: Some types of biomolecules found in plant cells can be also be found in animal cells. True False
A: Biomolecules are the molecules that are organic in nature and consists of carbon as main…
Q: Which of the following is not found within the cytoplasm of a cell? a) Plasma membrane b) Cytosol…
A:
Q: Which of the following statements is/are TRUE for transcription? A. RNA polymerase uses one strand…
A: Transcription is the process in which RNA is synthesized from DNA. This process involves certain…
Q: Phospholipase responsible for the tissue damage after spider bite? a.A1 b.A2 c.D d.C
A: Phospholipase (PLA) is a lipolytic enzymes which cleaves the phospholipid substrates at specific…
Q: Chymotrypsin is a digestive enzyme with a catalytic optimum between pH 7.8 and 8.0. However, due to…
A: Henderson-Hasselbalch equation relates pH, pKa and the ratio of concentrations of protonated to…
Q: Which of the following statements is/are TRUE about the PPP? A. Most active in cells where…
A: Which of the following statements is/are TRUE about the PPP? A. Most active in cells where…
Q: The amino acid histidine has ionizable groups with p?a values of 1.8, 6.0, and 9.2, as shown. A…
A: Amino acids are the building blocks of proteins which are composed of amino group (NH3+), carboxyl…
Step by step
Solved in 2 steps with 2 images
- 1. A certain polypeptide was treated with trypsin and yielded the following Fragments: Leu-Glu Gly-Tyr-Asn-Arg Gln-Ala-Phe-Val-Lys The same polypeptide was treated with chymotrypsin and yielded the following fragments: Gln-Ala-Phe Asn-Arg-Leu-Glu Val-Lys-Gly-Tyr What is the amino acid sequence of this polypeptide? Instructions Make use of the table below to determine the sequence of the mystery protein.2. Draw all three structures in the mutarotation equilibrium of (a) d-gulopyranose and also of (b) d- altropyranose. Look up the major structure found in this equilibrium and offer a brief explanation based on the anomeric effect.2. Amino acid analysis of the a heptapeptide gave the following residues: Asp Glu Leu Lys Met Tyr Trp NH4+ The following facts were observed: a) Trypsin treatment had no effect. b) The phenylthiohydantoin released by Edman degradation was -C-CH₂ What is the amino acid sequence for this heptapeptide? OH c) Brief chymotrypsin treatment yielded several products including a dipeptide and a tetrapeptide. The tetrapeptide contained Glu, Leu, Lys and Met is some order. d) Cyanogen bromide treatment afforded a tetrapeptide that had a net positive charge at pH 7 and tripeptide that had a zero net charge at pH 7.
- 1. Choose the proper structure of the predominant form of L-M-L-P-D-T at pH 5. Provide a short explanation. 2. Choose the proper structure of the predominant form of L-A-L-Y at pH 11. Provide a short explanation.2. Amino acid analysis of the a heptapeptide gave the following residues: Asp Glu Leu Lys Met Tyr Trp NH4+. The following facts were observed: Trypsin treatment had no effect. The phenylthiohydantoin released by Edman degradation was OH H C-C-CH₂ H. Brief chymotrypsin treatment yielded several products including a dipeptide and a tetrapeptide. The tetrapeptide contained Glu, Leu, Lys and Met is some order. Cyanogen bromide treatment afforded a tetrapeptide that had a net positive charge at pH 7 and tripeptide that had a zero net charge at pH 7. What is the amino acid sequence for this heptapeptide?2. Draw the structure of pentapeptide Trp-Asp-Cys-Lys-Gln that would predominate in aqueous solution at pH=5.5. (Relevant pKa values are 2.2, 3.8, 8.3, 9.6 and 10.5.)
- 9. The T conformation of the hemoglobin tetramer is stabilized (in part) by a salt linkage between the side chain of the lysine residue at position 40 in the a-chain of one aß dimer and the C-terminal carboxylate group of the ß-chain of the opposing aß dimer. Draw a diagram of this salt linkage (show complete side chains).15. Which of the following glycans can be released from proteins using BB- elimination? a. Complex N-linked glycans b. Glycosaminoglycans c. Mucin type O- glycans d Hyaluronic acid 16. Which of the following glycans are made by the addition of sugars to the reducing end of a growing glycan chain? a. Hyaluronan b. Heparan sulfate c. Mucin type O-glycans d. Gangliosides e. Cellulose 17 Name the following ganglioside using GNX nomenclature? 2002) Please draw a-mannose 1,4' B-talose.
- 1. Gemtuzumab and Trastuzumab emtansine are two examples of mAb-drug conjugates (ADCS) where the thiol-containing drugs calicheamicin and DM1, respectively, are attached to the mAb's via the linkers shown below. SO, Na „SH Thiolhydrazide in Gemtuzumab Sulfo-SMCC in Trastuzumab emtansine (i) Show the chemistry involved in conjugating the drug (Calicheamicin-SH) to the antibody in Gemtuzumab and draw the target mAb-drug conjugate with a detailed linker region. Show the chemistry involved in conjugating the drug (DM1-SH) to the antibody in Trastuzumab and draw the target mAb-drug conjugate with a detailed linker (ii) region.2. A mixture of the following amino acids (glu, leu, val, arg, ser, phe) was obtained upon complete hydrolysis of a hexapeptide. a. Edman’s reagent releases leucine b. Hexapeptide with carboxypeptidase releases serine. c. Hexapeptide with trypsin forms a tripeptide A with leucine at the N terminal and tripeptide B with valine at the N terminal. d. Tripeptide A with carboxypeptidase releases arginine and a dipeptide with glutamic acid at C terminal. e. Tripeptide B with chymotrypsin form releases serine and another dipeptide. Give: 1. the amino acid sequence of tripeptide A and B. 2. the amino acid sequence in the above hexapeptide.2. Of the two sequences, which is more likely to have helical structure. Explain. a) -Glu-Asp-Glu-Glu-Asp-Leu- b) -Glu-Leu-Asp-Arg-Val-Lys-